Current Issue March 2012, Vol. 36, No. 3

Issue Highlights

Invited Review

What do kinase inhibition profiles tell us about tyrosine kinase inhibitors used for the treatment of CML?
March 2012(Vol. 36 | No. 3 | Pages 253-261)
Michael W. Deininger, Paul Manley

Meeting Report

Update on developments in the diagnosis and prognostic evaluation of patients with myelodysplastic syndromes (MDS): Consensus statements and report from an expert workshop
March 2012(Vol. 36 | No. 3 | Pages 264-270)
Uwe Platzbecker, Valeria Santini, Ghulam J. Mufti, Claudia Haferlach, Jaroslaw P. Maciejewski, Sophie Park, Francesc Solé, Arjan A. van de Loosdrecht, Detlef Haase

Clinical Studies

Imatinib mesylate at therapeutic doses has no impact on folliculogenesis or spermatogenesis in a leukaemic mouse model
March 2012(Vol. 36 | No. 3 | Pages 271-274)
Beate Schultheis, Bart A. Nijmeijer, H. Yin, Roger G. Gosden, Junia V. Melo

A tribute to Professor Terence “Terry” John Hamblin
06 February 2012
John M. Bennett, Daniel Catovsky, David Bowen
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Abl-interactor 2 (ABI2): A novel MLL translocation partner in acute myeloid leukemia
03 February 2012
Eva A. Coenen, C. Michel Zwaan, Claus Meyer, Rolf Marschalek, Ursula Creutzig, Rob Pieters, Jutta Bradtke, Marry M. van den Heuvel-Eibrink
Mixed-Lineage Leukemia (MLL)-rearrangements are frequently involved in both adult and childhood acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). In childhood they are especially fr...
The clinical, quality of life, and economic consequences of chronic anemia and transfusion support in patients with myelodysplastic syndromes
02 February 2012
Uwe Platzbecker, Lorenz C. Hofbauer, Gerhard Ehninger, Kristina Hölig
Abstract: Most patients with myelodysplastic syndromes (MDS) require transfusions due to chronic anemia. Apart from the acute risks associated with transfusions, chronic anemia and red blood cell (RBC...
Differential diagnosis of paediatric bone pain: Acute lymphoblastic leukemia
30 January 2012
Nicolien van der Have, Shriram Vaidia Nath, Colin Story, Heather Tapp, C. Nicola, Sarah Moore, Rosemary Sutton, Tamas Revesz
Acute lymphoblastic leukemia (ALL) is the commonest malignancy in childhood. While most patients with ALL present with pallor or bleeding signs, some present with localized or diffuse bone pains and t...
Cytarabine in relapsed acute myeloid leukemia
30 January 2012
Brandon M. Hardesty, Larry D. Cripe
The majority of adults with acute myeloid leukemia (AML) in remission will experience a relapse of their disease. Dose-escalated cytarabine has been the mainstay in the treatment of adults with relaps...

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Prognostic significance of serum immunoglobulin paraprotein in patients with chronic lymphocytic leukemia
August 2011 (Vol. 35 | No. 8 | Pages 1060-1065)
Wei Xu, Yin-Hua Wang, Lei Fan, Cheng Fang, Dan-Xia Zhu, Dong-Mei Wang, Chun Qiao, Yu-Jie Wu, Jian-Yong Li
Can grapefruit juice decrease the cost of imatinib for the treatment of chronic myelogenous leukemia?
January 2011 (Vol. 35 | No. 1 | Pages e11-e12)
Shun-ichi Kimura, Shinichi Kako, Hidenori Wada, Kana Sakamoto, Masahiro Ashizawa, Miki Sato, Kiriko Terasako, Misato Kikuchi, Hideki Nakasone, Shinya Okuda, Rie Yamazaki, Kumi Oshima, Junji Nishida, Takuro Watanabe, Yoshinobu Kanda
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Alloreactive natural killer cells in hematopoietic stem cell transplantation
January 2011 (Vol. 35 | No. 1 | Pages 14-21)
Hollie J. Pegram, David S. Ritchie, Mark J. Smyth, Andres Wiernik, H. Miles Prince, Phillip K. Darcy, Michael H. Kershaw
Characteristics and outcome of myelodysplastic syndromes (MDS) with isolated 20q deletion: A report on 62 cases
July 2011 (Vol. 35 | No. 7 | Pages 863-867)
Thorsten Braun, Stéphane de Botton, Anne-Laure Taksin, Sophie Park, Odile Beyne-Rauzy, Valérie Coiteux, Rosa Sapena, Anne Lazareth, Geneviève Leroux, Khaled Guenda, Bruno Cassinat, Michaela Fontenay, Norbert Vey, Agnès Guerci, François Dreyfus, Dominique Bordessoule, Aspasia Stamatoullas, Sylvie Castaigne, Christine Terré, Virginie Eclache, Pierre Fenaux, Lionel Adès
MPN-associated myelofibrosis (MPN-MF)
January 2011 (Vol. 35 | No. 1 | Pages 12-13)
R.A. Mesa, A. Green, G. Barosi, S. Verstovsek, J. Vardiman, R.P. Gale
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Publishing Information

Leukemia Research is published by Elsevier.

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About Leukemia Research

Leukemia Research an international journal which brings comprehensive and current information to all health care professionals involved in basic and (or) applied clinical research in leukemias, lymphomas, multiple myeloma and other hematologic malignancies. The editors encourage the submission of articles relevant to normal and leukemic hemopoiesis, biochemistry, cell biology, immunology and molecular biology as well as epidemiologic and clinical studies.

Specifically, of major interest will be articles that encompass the application of oncogenes, growth factors, cell markers, cell cycle and differentiation agents, novel therapeutics and clinical trials in both the acute and chronic leukemias as well as the myelodysplastic syndromes. In addition we solicit selected articles on the rapidly increasing specialty of marrow or stem cell reconstitution after high dose therapy with curative attempt in patients with a wide range of neoplasms.

MDS Foundation Information

The MDS Foundation is a multidisciplinary, international organization devoted to the prevention, treatment, and study of the myelodysplastic syndromes. The organization is based upon the premise that international cooperation will accelerate the process leading to the control and cure of these diseases.