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Leukemia Research
Volume 34, Issue 4, Pages 409-552 (April 2010)

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Editorial Board
page CO2
Full-Text PDF (56 KB)

Guest Editorials


Right and left shifts for age in MDS
Semra Paydas
pages 409-410
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Captivating Bortezomib: An active but still mysterious drug
Francesco Di Raimondo, Concetta Conticello
pages 411-412
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Adding FISH to karyotype in Myelodysplastic syndrome investigation diagnosis: Are all questions answered?
Maria de Lourdes L.F. Chauffaille
pages 413-415
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Tumor suppression in T cell leukemia—The role of Ikaros
Sinisa Dovat, Kimberly J. Payne
pages 416-417
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Pediatric acute lymphoblastic leukemia: There is no TEL-ing what wonders lie ahead
Claudio Sandoval
pages 418-419
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Clinical Studies


FISH analysis in addition to G-band karyotyping: Utility in evaluation of myelodysplastic syndromes?
Wendy Yang, Brie Stotler, Deborah W. Sevilla, Foxwell N. Emmons, Vundavalli V. Murty, Bachir Alobeid, Govind Bhagat
pages 420-425
Abstract | Full Text | Full-Text PDF (139 KB)


Genetic inactivation of Ikaros is a rare event in human T-ALL
Ambroise Marçais, Robin Jeannet, Lucie Hernandez, Jean Soulier, François Sigaux, Susan Chan, Philippe Kastner
pages 426-429
Abstract | Full Text | Full-Text PDF (360 KB)


CD9 expression can be used to predict childhood TEL/AML1-positive acute lymphoblastic leukemia: Proposal for an accelerated diagnostic flowchart
Virginie Gandemer, Marc Aubry, Mikael Roussel, Anne-Gaelle Rio, Marie de Tayrac, Audrey Vallee, Jean Mosser, Béatrice Ly-Sunnaram, Marie-Dominique Galibert
pages 430-437
Abstract | Full Text | Full-Text PDF (969 KB) | Add-Ons


Acute lymphoplasmacytoid dendritic cell (DC2) leukemia: Results from the Hellenic Dendritic Cell Leukemia Study Group
Nikolaos J. Tsagarakis, Nektaria A. Kentrou, Konstantinos A. Papadimitriou, Maria Pagoni, Garyfallia Kokkini, Helen Papadaki, Vassiliki Pappa, Theodoros Marinakis, Nikolaos I. Anagnostopoulos, Chrissanthi Vadikolia, Achilleas Anagnostopoulos, Maria K. Angelopoulou, Evangelos Terpos, Christos Poziopoulos, Konstantinos Anargyrou, Dimitra Rontogianni, Theodora Papadaki, Aikaterini Psarra, Flora N. Kontopidou, Dimitra Skoumi, Stefanos I. Papadhimitriou, Georgios Paterakis, for the Hellenic Dendritic Cell Leukemia Study Group
pages 438-446
Abstract | Full Text | Full-Text PDF (625 KB)


FISH and SNP-A karyotyping in myelodysplastic syndromes: Improving cytogenetic detection of del(5q), monosomy 7, del(7q), trisomy 8 and del(20q)
Hideki Makishima, Manjot Rataul, Lukasz P. Gondek, Jungwon Huh, James R. Cook, Karl S. Theil, Mikkael A. Sekeres, Elizabeth Kuczkowski, Christine O’Keefe, Jaroslaw P. Maciejewski
pages 447-453
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Expression of the human concentrative nucleotide transporter 1 (hCNT1) gene correlates with clinical response in patients affected by Waldenström's Macroglobulinemia (WM) and small lymphocytic lymphoma (SLL) undergoing a combination treatment with 2-chloro-2′-deoxyadenosine (2-CdA) and Rituximab
C. Rabascio, D. Laszlo, G. Andreola, L. Saronni, D. Radice, L. Rigacci, A. Fabbri, F. Frigeri, L. Calabrese, A. Billio, F. Bertolini, G. Martinelli
pages 454-457
Abstract | Full Text | Full-Text PDF (212 KB)


Analyses on clinical characteristic and prognoses of 41 patients with chronic myelomonocytic leukemia in China
Bobin Chen, Yan Ma, Xiaoping Xu, Xiaoqin Wang, Wenjiao Qin, Meirong Ji, Guowei Lin
pages 458-462
Abstract | Full Text | Full-Text PDF (190 KB)


Elevated mRNA level of hST6Gal I and hST3Gal V positively correlates with the high risk of pediatric acute leukemia
Susmita Mondal, Sarmila Chandra, Chitra Mandal
pages 463-470
Abstract | Full Text | Full-Text PDF (520 KB)


Bortezomib-induced peripheral neuropathy in multiple myeloma: A comparison between previously treated and untreated patients
Alessandro Corso, Silvia Mangiacavalli, Marzia Varettoni, Cristana Pascutto, Patrizia Zappasodi, Mario Lazzarino
pages 471-474
Abstract | Full Text | Full-Text PDF (116 KB)


ALK-negative anaplastic large cell lymphoma with extensive peripheral blood and bone marrow involvements manifested as “leukemic phase”
Ying Lu, Xiaohui Zhao, Endi Wang, Wei Chen, Qin Huang
pages 475-482
Abstract | Full Text | Full-Text PDF (1338 KB)


T-cell lymphoblastic leukemia in early childhood presents NOTCH1 mutations and MLL rearrangements
Marcela Braga Mansur, Mariana Emerenciano, Alessandra Splendore, Lilian Brewer, Rocio Hassan, Maria S. Pombo-de-Oliveira, Brazilian Collaborative Study Group of Infant Acute Leukemia
pages 483-486
Abstract | Full Text | Full-Text PDF (129 KB)


Phase I trials of amonafide as monotherapy and in combination with cytarabine in patients with poor-risk acute myeloid leukemia
Steven L. Allen, Jonathan E. Kolitz, Ante S. Lundberg, John M. Bennett, Robert L. Capizzi, Daniel R. Budman
pages 487-491
Abstract | Full Text | Full-Text PDF (130 KB)


Polymorphisms in glucocorticoid receptor gene and the outcome of childhood acute lymphoblastic leukemia (ALL)
Malgorzata Labuda, Annabel Gahier, Vincent Gagné, Albert Moghrabi, Daniel Sinnett, Maja Krajinovic
pages 492-497
Abstract | Full Text | Full-Text PDF (565 KB)

Laboratory Studies


Proteasome inhibitor-induced apoptosis in acute myeloid leukemia: A correlation with the proteasome status
Mariette Matondo, Marie-Pierre Bousquet-Dubouch, Nathalie Gallay, Sandrine Uttenweiler-Joseph, Christian Recher, Bernard Payrastre, Stéphane Manenti, Bernard Monsarrat, Odile Burlet-Schiltz
pages 498-506
Abstract | Full Text | Full-Text PDF (735 KB) | Add-Ons


The role of p38 mitogen-activated protein kinase in serum-induced leukemia inhibitory factor secretion by bone marrow stromal cells from pediatric myelodysplastic syndromes
Simone V. da Costa, Rosimeire A. Roela, Mara Souza Junqueira, Camila Arantes, M. Mitzi Brentani
pages 507-512
Abstract | Full Text | Full-Text PDF (538 KB) | Add-Ons


All-trans retinoic acid inhibits the differentiation, maturation, and function of human monocyte-derived dendritic cells
Chun-Ji Jin, Cheol Yi Hong, Masao Takei, Sang-Young Chung, Jung-Sun Park, Thanh-Nhan Nguyen Pham, Soo-Jin-Na Choi, Jong-Hee Nam, Ik-Joo Chung, Hyeoung-Joon Kim, Je-Jung Lee
pages 513-520
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Multiple mechanisms induce ectopic expression of LYL1 in subsets of T-ALL cell lines
Stefan Nagel, Letizia Venturini, Corinna Meyer, Maren Kaufmann, Michaela Scherr, Hans G. Drexler, Roderick A.F. MacLeod
pages 521-528
Abstract | Full Text | Full-Text PDF (965 KB)


Functional analyses of Src-like adaptor (SLA), a glucocorticoid-regulated gene in acute lymphoblastic leukemia
Muhammad Mansha, Michela Carlet, Christian Ploner, Georg Gruber, Muhammad Wasim, Gerrit Jan Wiegers, Johannes Rainer, Stephan Geley, Reinhard Kofler
pages 529-534
Abstract | Full Text | Full-Text PDF (756 KB)


Synergistic effect of inhibiting translation initiation in combination with cytotoxic agents in acute myelogenous leukemia cells
Regina Cencic, Marilyn Carrier, Amanda Trnkus, John A. Porco, Mark Minden, Jerry Pelletier
pages 535-541
Abstract | Full Text | Full-Text PDF (694 KB) | Add-Ons

Brief Communications


Chronic myeloid leukemia: A disease of youth in Brazil
Mireille Guimarães Vaz de Campos, Adriano de Moraes Arantes, José Salvador Rodrigues de Oliveira, Maria de Lourdes Lopes Ferrari Chauffaille
pages 542-544
Full Text | Full-Text PDF (236 KB)


High body mass index is an independent predictor of differentiation syndrome in patients with acute promyelocytic leukemia
Ramzi Jeddi, Hèla Ghédira, Samia Mnif, Emna Gouider, Pierre Fenaux, Balkis Meddeb
pages 545-547
Abstract | Full Text | Full-Text PDF (109 KB)

Case of the Month


Primary mantle cell lymphoma of the thyroid
Salvatore Guastafierro, Umberto Falcone, Maria Celentano, Maria Giovanna Ferrara, Antonello Sica, Antonella Carbone, Raffaele Rossiello
pages 548-550
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Corrigendum


Corrigendum to “Prognostic significance of angiogenic/lymphangiogenic, anti-apoptotic, inflammatory and viral factors in 88 cases with diffuse large B cell lymphoma and review of the literature” [Leuk. Res. 33 (2009) 1627–1635] free full text
Semra Paydas, Melek Ergin, Gulsah Seydaoglu, Seyda Erdogan, Sinan Yavuz
page 551
Full Text | Full-Text PDF (72 KB)

Letter to the Editor


Anti-angiogenic strategies will be a revolution in lymphoma?
Semra Paydas
page 552
Full Text | Full-Text PDF (79 KB)

E-page Letters (available online only)


Paroxysmal nocturnal hemoglobinuria following alemtuzumab immunosuppressive therapy for myelodysplastic syndrome and complicated by recurrent life-threatening thrombosis despite anticoagulation: Successful intervention with eculizumab and fondaparinux Online Only
Kit L. Cheng, Judith Brody, Craig E. Warshall, Elaine M. Sloand, Steven L. Allen
pages e85-e87
Full Text | Full-Text PDF (97 KB)


Uterine chloroma, aortic thrombus and CALM/AF10 acute myeloid leukemia Online Only
Cécile Borel, Anne Huynh, Xavier Chaufour, Olivier Lousteau, Cécile Demur, Eric Delabesse, Paul Caverivière, Michel Attal, Christian Récher
pages e88-e90
Full Text | Full-Text PDF (712 KB)


Major molecular response achieved with dasatinib in a CML patient with F317L BCR-ABL kinase domain mutation Online Only
Edgar Faber, Renata Mojzikova, Radek Plachy, Sarka Rozmanova, Marek Stastny, Martina Divoka, Marie Jarosova, Karel Indrak, Vladimir Divoky
pages e91-e93
Full Text | Full-Text PDF (313 KB) | Add-Ons


A thrombocytosis occurring in Philadelphia positive CML in molecular response to imatinib can reveal an underlying JAK2V617F myeloproliferative neoplasm Online Only
L. Véronèse, A. Tchirkov, C. Richard-Pebrel, A. Ledoux-Pilon, J. Fleury, C. Chaleteix, C. Goumy, L. Gouas, M.G. Berger, P. Vago, J.O. Bay, O. Tournilhac
pages e94-e96
Full Text | Full-Text PDF (109 KB)


First report of a medullar cord compression secondary to osseous plasmacytoma successfully treated with bortezomib and dexamethasone Online Only
I. Español, A. Martínez, M.D. López, T. Iturbe, A. Tejedor, M.C. García, S. Cavero, C. Funes, J. Ibáñez
pages e97-e99
Abstract | Full Text | Full-Text PDF (313 KB)


A rare case of primary systemic amyloidosis of the neck with massive cervical lymph node involvement: A case report and review of the literature Online Only
V. Seccia, I. Dallan, G. Cervetti, R. Lenzi, M. Marchetti, A.P. Casani, L. Muscatello
pages e100-e103
Abstract | Full Text | Full-Text PDF (747 KB)


Clonal evolution at leukemic relapse of multiple myeloma (secondary plasma cell leukemia) responding to re-treatment with bortezomib-based therapy. A case record Online Only
Paolo Bernardeschi, Maria Teresa Pirrotta, Iolanda Montenora, Gloria Giustarini, Maria Immacolata Ferreri, Paolo Simi, Giammaria Fiorentini
pages e104-e105
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Description of a new BCR-ABL point mutation in a CML patient with evolution to lymphoid blast crisis Online Only
Paula O.M. Hokama, Juliana Capannacci, Newton Key Hokama, Marcelo Gil Cliquet, Mair Pedro Souza, Marcos Augusto Mauad, Vergílio A.R. Colturato
pages e106-e107
Full Text | Full-Text PDF (86 KB)


Primary non-Hodgkin lymphoma of cervix successfully treated with rituximab: Positron emission tomography images before and after therapy: A case report Online Only
Bala Basak Oven Ustaalioglu, Ahmet Bilici, Mesut Seker, Nesrin Canpolat, Nagihan Ozdemir, Taflan Salepci, Mahmut Gumus
pages e108-e110
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Allogenic bone marrow transplantation with fludarabine/busulfan16 conditioning regimen and dasatinib maintenance therapy for elderly Philadelphia-positive acute/advanced leukemia patients Online Only
Mio Yamamoto, Junya Kuroda, Hitoji Uchiyama, Tsutomu Kobayashi, Yasuhiko Tsutsumi, Muneo Ohshiro, Nana Sasaki, Yuji Shimura, Shinsuke Mizutani, Yosuke Matsumoto, Chihiro Shimazaki, Shigeo Horiike, Masafumi Taniwaki, Chihiro Shimazaki
pages e111-e112
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Isolated CNS relapse of CML after bone marrow transplantation Online Only
Anish Thomas, Constance K. Stein, Teresa C. Gentile, Chirag M. Shah
pages e113-e114
Full Text | Full-Text PDF (241 KB)


Chronic lymphocytic leukemia presenting with symptomatic peritoneal infiltration Online Only
Salvatore Guastafierro, Umberto Falcone, Maria Celentano, Antonella Carbone, Maria Giovanna Ferrara, Salvatore Cappabianca, Antonello Sica
pages e115-e116
Full Text | Full-Text PDF (172 KB)


Littoral cell angioma: A correctable cause of progressive pancytopenia in a patient with myelodysplastic syndrome Online Only
Jason Bierenbaum, Daisy V. Alapat, Carlos Godinez, Adrian E. Park, Xianfeng Frank Zhao, Maria R. Baer
pages e117-e119
Full Text | Full-Text PDF (675 KB)


Multiple lipoma with hyperlipidemia in a multiple myeloma patient treated with bortezomib/dexamethazone Online Only
Moritaka Gotoh, Toshihiko Kitahara, Juri Sakuta, Daigo Akahane, Kazuma Ohyashiki
pages e120-e121
Full Text | Full-Text PDF (207 KB)

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