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Editorial Board page CO2 Full-Text PDF (55 KB)
Invited Review
BCR-ABL tyrosine kinase inhibitors in the treatment of Philadelphia chromosome positive chronic myeloid leukemia: A review Xin An, Amit K. Tiwari, Yibo Sun, Pei-Rong Ding, Charles R. Ashby, Zhe-Sheng Chen pages 1255-1268 Abstract | Full Text | Full-Text PDF (328 KB)
Guest Editorial
Genetic variation and the risk of acute lymphoblastic leukemia Charles G. Mullighan pages 1269-1270 Full Text | Full-Text PDF (94 KB)
Clinical Studies
Genome-wide association study of childhood acute lymphoblastic leukemia in Korea Sohee Han, Kyoung-Mu Lee, Sue K. Park, Jong Eun Lee, Hyo Seop Ahn, Hee Young Shin, Hyoung Jin Kang, Hong Hoe Koo, Jong Jin Seo, Ji Eun Choi, Yoon-Ok Ahn, Daehee Kang pages 1271-1274 Abstract | Full Text | Full-Text PDF (183 KB) | Add-Ons
DNA repair XRCC1 Arg399Gln polymorphism alone, and in combination with CYP2E1 polymorphisms significantly contribute to the risk of development of childhood acute lymphoblastic leukemia Tugba Boyunegmez Tumer, Duygu Yilmaz, Cihan Tanrikut, Gurses Sahin, Gulen Ulusoy, Emel Arinç pages 1275-1281 Abstract | Full Text | Full-Text PDF (195 KB)
The MIF −173G/C polymorphism and risk of childhood acute lymphoblastic leukemia in a Chinese population Yao Xue, Hongyan Xu, Liucheng Rong, Qin Lu, Jie Li, Na Tong, Meilin Wang, Zhengdong Zhang, Yongjun Fang pages 1282-1286 Abstract | Full Text | Full-Text PDF (128 KB)
Differential cytogenomics and miRNA signature of the Acute Myeloid Leukaemia Kasumi-1 cell line CD34+38− compartment Laura Pedranzini, Federica Mottadelli, Simona Ronzoni, Franca Rossella, Manuela Ferracin, Ivana Magnani, Gaia Roversi, Patrizia Colapietro, Massimo Negrini, Pier Giuseppe Pelicci, Lidia Larizza pages 1287-1295 Abstract | Full Text | Full-Text PDF (787 KB)
FISH analysis of circulating CD34+ cells as a new tool for genetic monitoring in MDS: Verification of the method and application to 27 MDS patients Friederike Braulke, Julie Schanz, Klaus Jung, Katayoon Shirneshan, Kristina Schulte, Claudia Schuetze, Rainer Steffens, Lorenz Trümper, Detlef Haase pages 1296-1301 Abstract | Full Text | Full-Text PDF (367 KB) | Add-Ons
FLT3 and KIT mutated pediatric acute myeloid leukemia (AML) samples are sensitive in vitro to the tyrosine kinase inhibitor SU11657 Bianca F. Goemans, Christian M. Zwaan, Jacqueline Cloos, Desiree de Lange, Anne H. Loonen, Dirk Reinhardt, Karel Hählen, Brenda E.S. Gibson, Ursula Creutzig, Gertjan J.L. Kaspers pages 1302-1307 Abstract | Full Text | Full-Text PDF (209 KB)
Influence of high expression of Smac/DIABLO protein on the clinical outcome in acute myeloid leukemia patients Agnieszka Pluta, Agata Wrzesien-Kus, Barbara Cebula-Obrzut, Anna Wolska, Anna Szmigielska-Kaplon, Magdalena Czemerska, Piotr Pluta, Tadeusz Robak, Piotr Smolewski, Agnieszka Wierzbowska pages 1308-1313 Abstract | Full Text | Full-Text PDF (290 KB)
Combined analysis of minimal residual disease at two time points and its value for risk stratification in childhood B-lineage acute lymphoblastic leukemia Lei Cui, Zhigang Li, Minyuan Wu, Weijing Li, Chao Gao, Guoren Deng pages 1314-1319 Abstract | Full Text | Full-Text PDF (226 KB)
Circulating Ki-67 index in plasma as a biomarker and prognostic indicator in chronic lymphocytic leukemia Jean-Marie Bruey, Hagop Kantarjian, Wanlong Ma, Zeev Estrov, Chenhsiung Yeh, Amber Donahue, Heather Sanders, Susan O’Brien, Michael Keating, Maher Albitar pages 1320-1324 Abstract | Full Text | Full-Text PDF (231 KB)
Survivin is upregulated in myeloma cell lines cocultured with mesenchymal stem cells Xiaofang Wang, Zhiqing Zhang, Cheng Yao pages 1325-1329 Abstract | Full Text | Full-Text PDF (334 KB)
The efficacy and safety of the low-thalidomide dose CTD (cyclophosphamide, thalidomide, dexamethasone) regimen in patients with multiple myeloma—A report by the Polish Myeloma Study Group Anna Dmoszynska, Adam Walter-Croneck, Iwona Hus, Norbert Grzasko, Joanna Manko, Wieslaw Wiktor Jedrzejczak, Grzegorz Charlinski, Lidia Usnarska-Zubkiewicz, Aleksander Skotnicki, Teresa Wolska-Smolen, Jaroslaw Piszcz, Janusz Kloczko pages 1330-1335 Abstract | Full Text | Full-Text PDF (298 KB)
Abnormal phenotype of bone marrow plasma cells in patients with chronic myeloid leukemia undergoing therapy with Imatinib Giovanni Carulli, Elisa Cannizzo, Virginia Ottaviano, Giulia Cervetti, Gabriele Buda, Sara Galimberti, Claudia Baratè, Alessandra Marini, Mario Petrini pages 1336-1339 Abstract | Full Text | Full-Text PDF (193 KB)
Validation of the International Prognostic Scoring System (IPSS) for Waldenstrom's macroglobulinemia (WM) and the importance of serum lactate dehydrogenase (LDH) Efstathios Kastritis, Marie-Christine Kyrtsonis, Evdoxia Hadjiharissi, Argyris Symeonidis, Evridiki Michalis, Panagiotis Repoussis, Constantinos Tsatalas, Michael Michael, Anastasia Sioni, Zafiris Kartasis, Ekaterini Stefanoudaki, Michail Voulgarelis, Sossana Delimpasi, Maria Gavriatopoulou, Efstathios Koulieris, Dimitra Gika, Athanasios Zomas, Paraskevi Roussou, Nikolaos Anagnostopoulos, Theophanis Economopoulos, Evangelos Terpos, Konstantinos Zervas, Meletios A. Dimopoulos, on behalf of the Greek Myeloma Study Group pages 1340-1343 Abstract | Full Text | Full-Text PDF (191 KB)
Hypoplastic myelodysplastic syndrome (h-MDS) is a distinctive clinical entity with poorer prognosis and frequent karyotypic and FISH abnormalities compared to aplastic anemia (AA) Youngil Koh, Hye Ryun Lee, Eun Young Song, Hyun Kyoung Kim, Inho Kim, Seonyang Park, Myoung Hee Park, Byoung Kook Kim, Sung-Soo Yoon, Dong Soon Lee pages 1344-1350 Abstract | Full Text | Full-Text PDF (220 KB)
Laboratory Studies
Comparative analysis of MVA-CD40L and MVA-TRICOM vectors for enhancing the immunogenicity of chronic lymphocytic leukemia (CLL) cells Mary T. Litzinger, Kenneth A. Foon, Kwong-Yok Tsang, Jeffrey Schlom, Claudia Palena pages 1351-1357 Abstract | Full Text | Full-Text PDF (336 KB) | Add-Ons
Targeting integrin linked kinase and FMS-like tyrosine kinase-3 is cytotoxic to acute myeloid leukemia stem cells but spares normal progenitors Andrew L. Muranyi, Shoukat Dedhar, Donna E. Hogge pages 1358-1365 Abstract | Full Text | Full-Text PDF (270 KB) | Add-Ons
NFκB modulators in a model of glucocorticoid resistant, childhood acute lymphoblastic leukemia Lindsay Nicholson, Andrew G. Hall, Christopher P. Redfern, Julie Irving pages 1366-1373 Abstract | Full Text | Full-Text PDF (541 KB) | Add-Ons
Engineered regulatory T cells prevent graft-versus-host disease while sparing the graft-versus-leukemia effect after bone marrow transplantation Jiang Cao, Chong Chen, Lingyu Zeng, Li Li, Zhenyu Li, Kailin Xu pages 1374-1382 Abstract | Full Text | Full-Text PDF (1278 KB)
A fluorescent biomarker of the polyamine transport system to select patients with AML for F14512 treatment J.-P. Annereau, V. Brel, C. Dumontet, Y. Guminski, T. Imbert, M. Broussas, S. Vispé, S. Bréand, N. Guilbaud, J.-M. Barret, C. Bailly pages 1383-1389 Abstract | Full Text | Full-Text PDF (260 KB)
Differential NOD/SCID mouse engraftment of peripheral blood CD34+ cells and JAK2V617F clones from patients with myeloproliferative neoplasms Tsz-Kan Fung, Alice M.S. Cheung, Yok-Lam Kwong, Raymond Liang, Anskar Y.H. Leung pages 1390-1394 Abstract | Full Text | Full-Text PDF (211 KB) | Add-Ons
Brief Communication
Reversibility of renal failure in newly diagnosed patients with multiple myeloma and the role of novel agents Maria Roussou, Efstathios Kastritis, Dimitrios Christoulas, Magdalini Migkou, Maria Gavriatopoulou, Irini Grapsa, Erasmia Psimenou, Dimitra Gika, Evangelos Terpos, Meletios A. Dimopoulos pages 1395-1397 Abstract | Full Text | Full-Text PDF (123 KB)
Case of the Month
Persistent detection of a novel MLL–SACM1L rearrangement in the absence of leukemia Takeshi Mori, Noriyuki Nishimura, Daiichiro Hasegawa, Keiichiro Kawasaki, Yoshiyuki Kosaka, Kazuko Uchide, Tomoko Yanai, Akira Hayakawa, Yasuhiro Takeshima, Hisahide Nishio, Masafumi Matsuo pages 1398-1401 Abstract | Full Text | Full-Text PDF (304 KB)
E-page Letters (available online only)
Central nervous system involvement at second relapse in acute promyelocytic leukemia treated with ATRA and chemotherapy Bijender Kumar, Vineeta Sharma, Anita Chopra, Manoranjan Mahapatra, Ravi Kumar, Sandeep Mathur, Sudha Sazawal, Sunil Kumar, Renu Saxena pages e264-e265 Full Text | Full-Text PDF (190 KB)
Localized graft-versus-host disease of the skin provoked by radiotherapy Niels W.C.J. van de Donk, Marijke R. van Dijk, Henk M. Lokhorst pages e266-e267 Full Text | Full-Text PDF (366 KB)
A case of blast clearance on sorafenib in relapsed FLT3-ITD acute myeloid leukemia: Evidence of efficacy continues to mount Mark J. Fesler, John M. Richart, Paul J. Petruska pages e268-e269 Full Text | Full-Text PDF (85 KB)
Sorafenib induces sustained molecular remission in FLT3-ITD positive AML with relapse after second allogeneic stem cell transplantation without exacerbation of acute GVHD: A case report J. Winkler, D. Rech, S. Kallert, J. Rech, N. Meidenbauer, W. Roesler, A. Mackensen pages e270-e272 Full Text | Full-Text PDF (105 KB)
Facilitating studies of cell proliferation in chronic lymphocytic leukemia Derek C. Macallan, Julien Defoiche, Luc Willems pages e273-e274 Full Text | Full-Text PDF (89 KB)
Intravascular large B-cell lymphoma, an exclusively small vessel disease? A case report and review of literature Xin Yao, Ayman Saad, Christopher R. Chitambar pages e275-e277 Full Text | Full-Text PDF (206 KB)
Is there still a role for G-banding in CLL? Rosangela Pinheiro Gonçalves Machado, Jose Ajax Queiroz, Juliana Cordeiro de Sousa, Romelia Pinheiro Gonçalves, Silvia Maria Meira Magalhaes, Ronald Feitosa Pinheiro pages e278-e279 Full Text | Full-Text PDF (86 KB)
ABVD associated with imatinib for coexisting chronic myeloid leukaemia and relapsed Hodgkin lymphoma A. Ferrario, F. Radaelli, M. Goldaniga, F. Grifoni F, B. Olivero, F. Rossi, L. Baldini pages e280-e281 Full Text | Full-Text PDF (86 KB)
B-cell acute lymphoblastic leukemia as evolution of a 8p11 myeloproliferative syndrome with t(8;22)(p11;q11) and BCR-FGFR1 fusion gene Carmen Baldazzi, Ilaria Iacobucci, Simona Luatti, Emanuela Ottaviani, Giulia Marzocchi, Stefania Paolini, Monica Stacchini, Cristina Papayannidis, Carla Gamberini, Giovanni Martinelli, Michele Baccarani, Nicoletta Testoni pages e282-e285 Full Text | Full-Text PDF (726 KB) | Add-Ons
Overdose with 16,000mg of imatinib mesylate Emilie Dehours, Béatrice Riu, Baptiste Valle, Etienne Chatelut, Christian Recher, Olivier Fourcade, Françoise Huguet pages e286-e287 Full Text | Full-Text PDF (91 KB)
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