Leukemia Research
Volume 23, Issue 8 , Pages 719-721, August 1999

Secondary acute myeloid leukemia 4 years after the diagnosis of hairy cell leukemia: case report and review of the literature

Department of Medicine, Princess Margaret Hospital, 610 University Avenue, Toronto, Ont. M5G 2M9, Canada

Received 12 January 1999; accepted 15 March 1999.

Abstract 

A 49-year-old man diagnosed with hairy cell leukemia (HCL) achieved a complete remission lasting 4 years after treatment with cladrabine and subsequently developed acute myeloid leukemia. Although a wide variety of second malignancies have been noted in HCL with an incidence of 8.7%, acute myeloid leukemia (AML) has been reported only once previously in a splenectomized patient who had been treated with alpha interferon.

Keywords: Hairy cell leukemia, Cladrabine, Acute myeloid leukemia, Secondary malignancy

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PII: S0145-2126(99)00090-9

Leukemia Research
Volume 23, Issue 8 , Pages 719-721, August 1999

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