Leukemia Research
Volume 33, Issue 11 , Pages 1574-1577 , November 2009

Aleukemic bcr-abl positive granulocytic sarcoma

  • Jew-Win Kuan

      Affiliations

    • Hematology Department, Ampang Hospital, Jalan Mewah Utara, Pandan Mewah, 68000 Ampang, Selangor, Malaysia
    • Corresponding Author InformationCorresponding author. Tel.: +60 198593011; fax: +60 362501864.
    • ,
  • Rajadurai Pathmanathan

      Affiliations

    • Pathology Department, Sime Darby Medical Centre Subang Jaya, 1, Jalan SS 12/1A, 47500 Subang Jaya, Selangor, Malaysia
    • ,
  • Kian-Meng Chang

      Affiliations

    • Hematology Department, Ampang Hospital, Jalan Mewah Utara, Pandan Mewah, 68000 Ampang, Selangor, Malaysia
    • ,
  • Sen-Moi Tan

      Affiliations

    • Hematology Department, Ampang Hospital, Jalan Mewah Utara, Pandan Mewah, 68000 Ampang, Selangor, Malaysia

Received 27 October 2008 ,Revised 13 January 2009 ,Accepted 15 January 2009.

References 

  1. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri ASHS, et al. WHO classification of tumours of haematopoietic and lymphoid tissues. 4th ed.. Lyon: IARC Press; 2008;
  2. Burns A. Observations on the surgical anatomy of the head and neck. Edinburgh: Bryce; 1811;pp. 364–7
  3. King A. Case of chloroma. Monthly J Med Sci (London). 1853; 7:97.
  4. Jaffe ES, Harris NL, Stein H, Vardiman JW. Pathology and genetics of tumours of haematopoietic and lymphoid tissues. IARC, WHO; 2001;
  5. Muss HB, Moloney WC. Chloroma and other myeloblastic tumors. Blood. 1973;42(5):721–728
  6. Bekassy AN, Hermans J, Gorin NC, Gratwohl A. Granulocytic sarcoma after allogeneic bone marrow transplantation: a retrospective European multicenter survey Acute and Chronic Leukemia Working Parties of the European Group for Blood and Marrow Transplantation. Bone Marrow Transpl. 1996;17(5):801–808
  7. Neiman RS, Barcos M, Berard C, Bonner H, Mann R, Rydell RE, et al. Granulocytic sarcoma: a clinicopathologic study of 61 biopsied cases. Cancer. 1981;48(6):1426–1437Sep 15
  8. Huang CS, Gomez GA, Kohno SI, Sokal JE, Sandberg AA. Chromosomes and causation of human cancer and leukemia. XXXIV. A case of “hypereosinophilic syndrome” with unusual cytogenetic findings in a chloroma, terminating in blastic transformation and CNS leukaemia. Cancer. 1979;44(4):1284–1289
  9. Cheah KL, Lim LC, Teong HH, Chua SH. A case of generalised cutaneous granulocytic sarcoma in an elderly patient with myelodysplastic syndrome. Singapore Med J. 2002;43(10):527–529
  10. List AF, Gonzalez-Osete G, Kummet T, Doll DC. Granulocytic sarcoma in myelodysplastic syndromes: clinical marker of disease acceleration. Am J Med. 1991;90(2):274–276
  11. Pileri SA, Ascani S, Cox MC, Campidelli C, Bacci F, Piccioli M, et al. Myeloid sarcoma: clinico-pathologic, phenotypic and cytogenetic analysis of 92 adult patients. Leukemia. 2007;21(2):340–350
  12. Martinelli G, Ottaviani E, Testoni N, Visani G, Pagliani G, Tura S. Molecular analysis of granulocytic sarcoma: a single center experience. Haematologica. 1999;84(4):380–382
  13. Paydas S, Zorludemir S, Ergin M. Granulocytic sarcoma: 32 cases and review of the literature. Leuk Lymphoma. 2006;47(12):2527–2541
  14. Vassallo J, Altemani AM, Cardinalli IA, Crespo AN, Lima CS, Eid KA, et al. Granulocytic sarcoma of the larynx preceding chronic myeloid leukemia. Pathol Res Pract. 1993;189(9):1084–1086discussion 6–9
  15. Ahmed S, Anwar M, Siddiqui SA, Saleem M, Ahmad PA, Mushtaq S. Granulocytic sarcoma in patients with chronic myeloid leukaemia. J Pak Med Assoc. 1995;45(7):180–181
  16. Jenkins CI, Sorour Y. Case report: a large extramedullary granulocytic sarcoma as the initial presenting feature of chronic myeloid leukemia. MedGenMed. 2005;7(4):23
  17. Sekiguchi N, Watanabe T, Kobayashi Y, Inokuchi C, Kim SW, Yokota Y, et al. The application of molecular analyses for primary granulocytic sarcoma with a specific chromosomal translocation. Int J Hematol. 2005;82(3):210–214
  18. Al-Quran SZ, Olivares A, Lin P, Stephens TW, Medeiros LJ, Abruzzo LV. Myeloid sarcoma of the urinary bladder and epididymis as a primary manifestation of acute myeloid leukemia with inv(16). Arch Pathol Lab Med. 2006;130(6):862–866
  19. Xavier SG, Fagundes EM, Hassan R, Bacchi C, Conchon M, Tabak DG, et al. Granulocytic sarcoma of the small intestine with CBFbeta/MYH11 fusion gene: report of an aleukaemic case and review of the literature. Leuk Res. 2003;27(11):1063–1066
  20. Lee DA, Harris CP, Gresik VM, Rao P, Lau CC. Granulocytic sarcoma presenting as pneumonia in a child with t(8;21) acute myelogenous leukemia: diagnosis by fluorescent in situ hybridization. J Pediatr Hematol Oncol. 2004;26(7):431–434
  21. Ahmed MS, Kroft SH, Davis NB, King DM, Cheng YC. Long-term remission with imatinib mesylate in Philadelphia chromosome-positive AML presenting as primary extramedullary myeloid sarcoma. Leuk Res. 2008;32(9):1476–1479
  22. Cividin M, Brizard F, Sorel N, Renaud M, Guilhot F, Brizard A. p190(BCR-ABL) rearrangement as a secondary change in a case of acute myelo-monocytic leukemia with inv(16)(p13q22). Leuk Res. 2004;28(1):97–99
  23. Roumier C, Daudignon A, Soenen V, Dupriez B, Wetterwald M, Lai JL, et al. p190 bcr-abl rearrangement: a secondary cytogenetic event in some chronic myeloid disorders?. Haematologica. 1999;84(12):1075–1080
  24. Yagyu S, Morimoto A, Kakazu N, Tamura S, Fujiki A, Nakase Y, et al. Late appearance of a Philadelphia chromosome in a patient with therapy-related acute myeloid leukemia and high expression of EVI1. Cancer Genet Cytogenet. 2008;180(January(2)):115–120
  25. Akel S, Kolialexi A, Mavrou A, Metaxotou C, Loukopoulos D, Yataganas X. Efficiency of interphase fluorescence in situ hybridization for BCR/ABL on peripheral blood smears for monitoring of CML patients: a comparison with bone marrow findings. Clin Lab Haematol. 2002;24(6):361–367
  26. Kiss TL, Xu WM, Jamal N, Messner HA. Comparative testing of peripheral blood and bone marrow for BCR-ABL transcripts in patients post allogeneic bone marrow transplantation and during interferon treatment for chronic myeloid leukemia. Leuk Lymphoma. 1999;34(5–6):493–500
  27. Reinhold U, Hennig E, Leiblein S, Niederwieser D, Deininger MW. FISH for BCR-ABL on interphases of peripheral blood neutrophils but not of unselected white cells correlates with bone marrow cytogenetics in CML patients treated with imatinib. Leukemia. 2003;17(10):1925–1929
  28. Oren H, Yilmaz S, Sercan Z, Demircioglu F, Yuksel E, Irken G. Isolated myelosarcoma development in an adolescent chronic myeloid leukemia patient with t(9;22)(q34;q11.2), +8, +14, +21, and der(1)(p36). Cancer Genet Cytogenet. 2008;182(April(1)):43–45
  29. Rosario Cavalheiro Rde C, Vicari P, Maria Morselli F, Ommati LV, Frazao Rosa Fde O, Rodrigues Oliveira JS. Granulocytic sarcoma giant in chronic myeloid leukemia during imatinib mesylate therapy. Am J Hematol. 2006;81(1):76–77

PII: S0145-2126(09)00023-X

doi: 10.1016/j.leukres.2009.01.016

Leukemia Research
Volume 33, Issue 11 , Pages 1574-1577 , November 2009

Article Tools

* Image Usage & Resolution