Leukemia Research
Volume 32, Issue 2 , Pages 263-267 , February 2008

CD45 expression in low-grade B-cell non-Hodgkin's lymphomas

  • Giovanni Carulli

      Affiliations

    • Division of Hematology, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Italy
    • Corresponding Author InformationCorresponding author at: Division of Hematology, Santa Chiara Hospital, Via Roma 67, I-56126 Pisa, Italy. Tel.: +39 050 992185; fax: +39 050 992185.
    • ,
  • Elisa Cannizzo

      Affiliations

    • Division of Hematology, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Italy
    • ,
  • Alessandra Zucca

      Affiliations

    • Division of Hematology, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Italy
    • ,
  • Gabriele Buda

      Affiliations

    • Division of Hematology, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Italy
    • ,
  • Enrico Orciuolo

      Affiliations

    • Division of Hematology, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Italy
    • ,
  • Alessandra Marini

      Affiliations

    • Laboratory of Clinical Pathology, Section of Flow Cytometry, Ospedale Unico della Versilia, Lido di Camaiore, Italy
    • ,
  • Mario Petrini

      Affiliations

    • Division of Hematology, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa, Italy

Received 8 April 2007 ,Revised 7 June 2007 ,Accepted 12 June 2007.

References 

  1. Serra-Pages C, Morimoto C, Schlossman SF, et al. Characterization of CD45 mAb. In:  Schlossman SF,  Bournsell L,  Gilks W, et al. editor. Leucocyte typing V: white cell differentiation antigens. Oxford: Oxford University Press; 1995;p. 389–391
  2. Stelzer GT, Shults KE, Loken MR. CD45 gating for routine flow cytometric analysis of human bone marrow specimens. Ann NY Acad Sci. 1993;677:265–280
  3. Borowitz MJ, Guenther KL, Shult KE, Steltzer GT. Immunophenotyping of acute leukemia by flow cytometric analysis: use of CD45 and right-angle light scatter to gate on leukemic blasts in three-color analysis. Am J Clin Pathol. 1993;100:534–540
  4. Shah VO, Civin CI, Loken MR. Flow cytometric analysis of human bone marrow. IV. Differential quantitative expression of T-200 common leukocyte antigen during normal hemopoiesis. J Immunol. 1988;140:1861–1867
  5. McKenna R, Washington LT, Aquino DB, et al. Immunophenotypic analysis of hematogones (B-lymphocyte precursors) in 662 consecutive bone marrow specimens by 4-color flow cytometry. Blood. 2001;98:2498–2507
  6. Caldwell C-W, Patterson W-P. Relationship between CD45 antigen expression and putative stages of differentiation in B-cell malignancies. Am J Hematol. 1991;36:111–115
  7. Behm FG, Raimondi SC, Schell MJ, et al. Lack of CD45 antigen on blast cells in childhood leukemia is associated with chromosomal hyperdyploidity and other favorable prognostic features. Blood. 1992;79:1011–1016
  8. Inaba T, Shimazaki C, Sumikuma T, et al. CD45-negative acute leukemia in adulthood. Eur J Haematol. 2000;64:66–67
  9. Hendricks A, Bossuyt X. Quantification of the leukocyte common antigen (CD45) in mature B-cell malignancies. Cytometry. 2001;46:336–339
  10. Maljaei SH, Asvadi-e-Kermani I, Eivazi-e-Ziaei J, et al. Usefulness of CD45 density in the diagnosis of B-cell chronic lymphoproliferative disorders. Indian J Med Sci. 2005;59:187–194
  11. Harris NL, Jaffe ES, Stein H, et al. A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study group. Blood. 1994;84:1361–1392
  12. Carulli G, Canigiani S, Volpini M, et al. Bone marrow infiltration in B-cell non-Hodgkin's lymphomas: comparison between flow cytometry and bone marrow biopsy. Recent Prog Med. 2005;96:284–290
  13. Reed TJ, Reid A, Wallberg K, et al. Determination of B-cell clonality in paraffin-embedded lymph nodes using the polymerase chain reaction. Diagn Mol Pathol. 1993;2:42–49
  14. Ritter JH, Wick MR, Adesokan PN, et al. Assessment of clonality in cutaneous lymphoid infiltrates by polymerase chain reaction analysis of immunoglobulin heavy chain gene rearrangement. Am J Clin Pathol. 1997;108:60–68
  15. Willems P, Verhagen O, Segeren C, et al. Consensus strategy to quantitate malignant cells in myeloma patients is validated in a multicenter study. Blood. 2000;96:63–70
  16. Van Dongen JJ, Langerak AW, Bruggemann M, et al. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia. 2003;17:2257–2317
  17. Tytherleigh L, Taparia M, Leahy MF. Detection of hairy cell leukaemia in blood and bone marrow using multidimensional flow cytometry with CD45-PECy5 and SSC gating. Clin Lab Haematol. 2001;23:385–390
  18. Kraan J, Gratama JW, Keeney M, D’Hautcourt JL. Setting up and calibration of a flow cytometer for multicolour immunophenotyping. J Biol Regul Homeost Agents. 2003;223–233
  19. Lavabre-Bertrand T, Duperray C, Brunet C, et al. Quantification of CD24 and CD45 in parallel allows a precise determination of B-cell maturation stages: relevance for the study of B-cell neoplasias. Leukemia. 1994;8:402–408
  20. Caldwell C-W, Patterson W-P. Relationship between T200 antigen expression and stages of B-cell differentiation in resurgent hyperplasia of bone marrow. Blood. 1987;70:1165–1172
  21. Vallespì T, Monserrat E, Sanz MA. Chronic lymphocytic leukaemia: prognostic value of lymphocyte morphological subtypes: a multivariate analysis in 146 patients. Br J Haematol. 1991;77:478–485
  22. Oscier DG, Matutes E, Copplestone A, et al. Atypical lymphocyte morphology: an adverse prognostic factor for disease progression in stage A CLL independent of trisomy 12. Br J Haematol. 1997;98:934–939
  23. Matutes EJ, Owusu-Ankomah K, Morilla AM, et al. The immunological profile of B-cell disorders and proposal for a scoring system for the diagnosis of CLL. Leukemia. 1994;8:1640–1645
  24. Ratei R, Karawajew L, Lacombe F, et al. Normal lymphocytes from leukemic samples as an internal quality control for fluorescence intensity in immunophenotyping of acute leukemia. Cytometry. 2005;70B:1–9
  25. Schlette E, Fu K, Medeiros LJ. CD23 expression in mantle cell lymphoma: clinicopathologic features of 18 cases. Am J Clin Pathol. 2003;120:760–766
  26. Barry TS, Jaffe ES, Kingma DW, Martin AW, Sorbara L, Raffeld M, et al. CD5+ follicular lymphoma: a clinicopathologic study of three cases. Am J Clin Pathol. 2002;118:589–598
  27. Nelson BP, Variakojis D, Peterson LC. Leukemic phase of B-cell lymphomas mimicking chronic lymphocytic leukemia and variants at presentation. Mod Pathol. 2002;15:1111–1120
  28. Sheikh SS, Kallakury BV, Al-Kuraya KA, et al. CD5-negative, CD10-negative small B-cell leukemia: variant of chronic lymphocytic leukemia or a distinct entity?. Am J Hematol. 2002;71:306–310

PII: S0145-2126(07)00244-5

doi: 10.1016/j.leukres.2007.06.002

Leukemia Research
Volume 32, Issue 2 , Pages 263-267 , February 2008

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