Leukemia Research
Volume 30, Issue 7 , Pages 841-848 , July 2006

Ganoderma lucidum causes apoptosis in leukemia, lymphoma and multiple myeloma cells

  • Claudia I. Müller

      Affiliations

    • Cedars-Sinai Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States
    • Division of Haematology/Oncology, University Hospital, Freiburg, Germany
    • Corresponding Author InformationCorresponding author at: Division of Hematology/Oncology, Davis Building 5065, Cedars-Sinai Medical Center, David Geffen School of Medicine at UCLA, 8700 Beverly Boulevard, Los Angeles, CA 90048, United States. Tel.: +1 310 423 7759; fax: +1 310 423 0225.
    • ,
  • Takashi Kumagai

      Affiliations

    • Cedars-Sinai Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States
    • ,
  • James O’Kelly

      Affiliations

    • Cedars-Sinai Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States
    • ,
  • Navindra P. Seeram

      Affiliations

    • Center for Human Nutrition, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States
    • ,
  • David Heber

      Affiliations

    • Center for Human Nutrition, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States
    • ,
  • H. Phillip Koeffler

      Affiliations

    • Cedars-Sinai Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States

Received 4 May 2005 ,Revised 5 December 2005 ,Accepted 6 December 2005.

References 

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  2. Lin SB, Li CH, Lee SS, Kan LS. Triterpene-enriched extracts from Ganoderma lucidum inhibit growth of hepatoma cells via suppressing protein kinase C, activating mitogen-activated protein kinases and G2-phase cell cycle arrest. Life Sci. 2003;72:2381–2390
  3. Sliva D, Sedlak M, Slivova V, Valachovicova T, Lloyd FP, Ho NW. Biologic activity of spores and dried powder from Ganoderma lucidum for the inhibition of highly invasive human breast and prostate cancer cells. J Altern Complement Med. 2003;9:491–497
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  17. Kimura Y, Taniguchi M, Baba K. Antitumor and antimetastatic effects on liver of triterpenoid fractions of Ganoderma lucidum: mechanism of action and isolation of an active substance. Anticancer Res. 2002;22:3309–3318
  18. Fernandez C, Lobo M, Gomez-Coronado D, Lasuncion MA. Cholesterol is essential for mitosis progression and its deficiency induces polyploid cell formation. Exp Cell Res. 2004;300:109–120
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PII: S0145-2126(05)00473-X

doi: 10.1016/j.leukres.2005.12.004

Leukemia Research
Volume 30, Issue 7 , Pages 841-848 , July 2006

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