« Previous
Next »
Leukemia Research
Volume 30, Issue 4
, Pages 379-383
, April 2006
Low p53 expression of acute myelocytic leukemia cells with t(8;21) chromosome abnormality: Association with low p14ARF expression
References
- . Identification of a translocation with quinacrine fluorescence in a patient with acute leukemia. Ann Genet. 1973;16:109–112
- . C–G translocation in acute myelocytic leukemia with low neutrophil alkaline phosphatase activity. Cancer. 1976;37:2380–2387
- . Translocation (8;21) (q22;q22) in acute nonlymphocytic leukaemia. Fourth International Workshop on Chromosomes in Leukemia, 1982. Cancer Genet Cytogenet. 1984;11:284–287
- Isolation of a yeast artificial chromosome spanning the 8;21 translocation breakpoint t(8;21) (q22;q22.3) in acute myelogenous leukemia. Proc Natl Acad Sci USA. 1991;88:4882–4886
- . t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1. Proc Natl Acad Sci USA. 1991;88:10431–10434
- Identification of breakpoints in t(8;21) acute myelogeous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophia segmentation gene, runt. Blood. 1992;80:1825–1831
- The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript. EMBO J. 1993;12:2715–2721
- Identification of a region which directs monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1). Mol Cell Biol. 1994;14:8085–8095
- . PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2b/CBFb proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells. Mol Cell Biol. 1994;14:5558–5568
- . AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell. 1996;84:321–330
- . Distribution of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis. Proc Natl Acad Sci USA. 1996;93:3444–3449
- Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukaemia. Proc Natl Acad Sci USA. 1995;92:4917–4921
- Generation of the AML1-EVI-1 fusion gene in the t(3;21) (q26;q22) causes blastic crisis in chronic myelocytic leukaemia. EMBO J. 1994;13:504–510
- Biallelic and heterozygous point mutations in the runt domain of the AML1/PEBP2alphaB gene associated with myeloblastic leukemias. Blood. 1999;93:1817–1824
- Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia. Nat Genet. 1999;23:166–175
- High incidence of biallelic point mutations in the Runt domain of the AML1/PEBP2 alpha B gene in Mo acute myeloid leukemia and in myeloid malignancies with acquired trisomy 21. Blood. 2000;96:2862–2869
- Low BCL-2 expression in acute leukemia with t(8;21) chromosomal abnormality. Leukemia. 1999;13:358–368
- The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia. Nat Med. 2002;8:743–750
- . The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell. 1992;69:1237–1245
- . Establishment of a human acute myeloid leukemia cell line (Kasumi-1) with 8;21 chromosomal translocation. Blood. 1991;77:2031–2036
- . Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc Natl Acad Sci USA. 1992;89:7491–7495
- The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. EMBO J. 1998;17:5001–5014
- . An activated receptor tyrosine kinase, TEL/PDGFbetaR, cooperates with AML1/ETO to induce acute myeloid leukemia in mice. Proc Natl Acad Sci USA. 2003;100:9506–9511
- AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: implication in stepwise leukemogenesis and response to Gleevec. Proc Natl Acad Sci USA. 2005;102:1104–1109
PII: S0145-2126(05)00315-2
doi: 10.1016/j.leukres.2005.08.007
© 2005 Elsevier Ltd. All rights reserved.
« Previous
Next »
Leukemia Research
Volume 30, Issue 4
, Pages 379-383
, April 2006
