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Leukemia Research
Volume 29, Issue 8
, Pages 859-861
, August 2005
Multiple effects of Bioflavonoids on gene regulation, cell proliferation and apoptosis: Natural compounds move into the lime light of cancer research
References
- . Vitamin nature of flavones. Nature. 1936;138:798
- . Crystal and molecular structures of flavonoids. Prog Clin Biol Res. 1988;280:29
- . Effects of flavonoids and Vitamin C on oxidative DNA damage to human lymphocytes. Am J Clin Nutr. 1998;67:1210
- . Mechanisms of action of the soy isoflavone genistein: emerging role for its effects via transforming growth factor beta signaling pathways. Am J Clin Nutr. 1998;68:1418S
- . Phyto-oestrogens and western diseases. Ann. Med. 1997;29:95
- . Silibinin prevent photocarcinogenesis, which involves the inhibition of DNA synthesis, cell proliferation, and cell cycle progression and an induction of apoptosis. Cancer Res. 2004;64:6349
- . Docking studies and model development of tea polyphenol proteasome inhibitors: applications to rational drug design. Proteins. 2004;54:58
- Blocking telomerase by dietary polyphenols is a major mechanism for limiting the growth of human cancer cells in vitro and in vivo. Cancer Res. 2003;15:824
- . Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia. Proc Natl Acad Sci. 2000;97:4790
- . Quercetin inhibits tyrosine phosphorylation by the cyclic nucleotide-independent, transforming protein kinase, pp60src. Naunyn Schmiedebergs Arch Pharmacol. 1981;317:100
- . Effects of genistein on the growth and cell cycle progression of normal human lymphocytes and human leukemic MOLT-4 and HL-60 cells. Cancer Res. 1992;52:6200
- . Induction of apoptosis by quercetin: involvement of heat shock protein. Cancer Res. 1994;54:4952
- Dietary bioflavonoids induce apoptosis in human leukemia cells. Leuk Res. 2005;29:573
- . The role of activated MEK-ERK pathway in quercetin-induced growth inhibition and apoptosis in A549 lung cancer cells. Carcinogenesis. 2004;25:647
- . Induction of cancer cell apoptosis by flavonoids is associated with their ability to inhibit fatty acid synthase activity. J Biol Chem. 2005;280:5636
- . Dietary agents in cancer prevention: flavonoids and isoflavonoids. Pharmacol Ther. 2001;90:157
- . Green tea polyphenols and cancer chemoprevention: multiple mechanisms and endpoints for phase II trials. Nutr Rev. 2004;62:204
- . Case-control study of phyto-oestrogens and breast cancer. Lancet. 1997;350:990
- . Eating to beat breast cancer: potential role for soy supplements. Ann Oncol. 1997;8:223
- . Tamoxifen and genistein synergistically down-regulate signal transduction and proliferation in estrogen receptor-negative human breast carcinoma MDA-MB-435 cells. Anticancer Res. 1999;19:1657
- . Influence of drinking green tea on breast cancer malignancy among Japanese patients. Jpn J Cancer Res. 1998;89:254
- Flavopiridol binds to duplex DNA. Cancer Res. 2000;60:2419
- . Small-molecule cyclin-dependent kinase modulators. Oncogene. 2003;22:6609
- Phase I clinical trial of the flavonoid quercetin: pharmacokinetics and evidence for in vivo tyrosine kinase inhibition. Clin Cancer Res. 1996;2:659
- Ferry DR, Anderson M, Beddows K, Mayer P, Price L, Jankowski J. Phase II trial of gefitinib (ZD1839) in advanced adenocarcinoma of the oesophagus incorporating biopsy before and after gefitinib. 2004 ASCO Annual Meeting Proceedings (Post-Meeting Edition), J Clin Oncol 2004;22(14S):4021.
- . Anticancer therapeutic potential of soy isoflavone, genistein. Adv Exp Med Biol. 2004;546:121
- . VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukaemia. Blood. 2004;104:788
- . Research of complementary/alternative medicine therapies in oncology: promising but challenging. J Clin Oncol. 1999;17:38
- Soy isoflavonoids and cancer—metabolism at the target site. Mutat Res. 2001;480-481:121
- . International workshop on the relationship of prior therapy to balanced chromosome aberrations in therapy-related myelodysplastic syndromes and acute leukemia: overview report. Genes Chromosomes Cancer. 2002;33:331
☆ This editorial is linked to the article by Matsui et al. Dietary bioflavonoids induce apoptosis in human leukemia cells. Leuk Res 2005;29(5):573–82.
PII: S0145-2126(05)00196-7
doi: 10.1016/j.leukres.2005.01.022
© 2005 Elsevier Ltd. All rights reserved.
« Previous
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Leukemia Research
Volume 29, Issue 8
, Pages 859-861
, August 2005
