Leukemia Research
Volume 29, Issue 8 , Pages 923-931 , August 2005

JAK–STAT signaling involved in phorbol 12-myristate 13-acetate- and dimethyl sulfoxide-induced 2′-5′ oligoadenylate synthetase expression in human HL-60 leukemia cells

  • Shenhav Cohen

      Affiliations

    • Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel
  • ,
  • Sara Dovrat

      Affiliations

    • Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel
  • ,
  • Ronit Sarid

      Affiliations

    • Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel
    • Corresponding Author InformationCorresponding author. Tel.: +972 3 5317853; fax: +972 3 5351824.
  • ,
  • Eliezer Huberman

      Affiliations

    • Biochip Technology Center, Argonne National Laboratory, Argonne, IL 60439-4833, USA
  • ,
  • Samuel Salzberg

      Affiliations

    • Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 52900, Israel
    • Deceased (1940–2000).

Received 6 December 2004 ,Revised 20 January 2005 ,Accepted 31 January 2005.

References 

  1. Darnell JE, Kerr IM, Stark GR. JAK–STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science. 1994;264:1415–1421
  2. Ihle JN, Witthuhn BA, Quelle FW, Yamamoto K, Thierfelder WE, Kreider B, et al. Signaling by the cytokine receptor superfamily: JAKs and STATs. Trends Biochem Sci. 1994;19:222–227
  3. Naka T, Fujimoto M, Kishimoto T. Negative regulation of cytokine signaling: STAT-induced STAT inhibitor. Trends Biochem Sci. 1999;24:394–398
  4. Aaronson DS, Horvath CM. A road map for those who don’t know JAK–STAT. Science. 2002;296:1653–1655
  5. Kerr IM, Costa-Pereira AP, Lillemeier BF, Strobl B. Of JAKs, STATs, blind watchmakers, jeeps and trains. FEBS Lett. 2003;546:1–5
  6. Velazquez L, Fellous M, Stark GR, Pellegrini S. A protein tyrosine kinase in the interferon alpha/beta signaling pathway. Cell. 1992;70:313–322
  7. Collins SJ, Ruscetti FW, Gallagher RE, Gallo RC. Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds. Proc Natl Acad Sci USA. 1978;75:2458–2462
  8. Forsbeck K, Nilsson K, Hansson A, Skoglund G, Ingelman-Sundberg M. Phorbol ester-induced alteration of differentiation and proliferation in human hematopoietic tumor cell lines: relationship to the presence and subcellular distribution of protein kinase C. Cancer Res. 1985;45:6194–6199
  9. Liu WS, Heckman CA. The sevenfold way of PKC regulation. Cell Signal. 1998;10:529–542
  10. Breitman TR, Selonick SE, Collins SJ. Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid. Proc Natl Acad Sci USA. 1980;77:2936–2940
  11. Huberman E, Callaham MF. Induction of terminal differentiation in human promyelocytic leukemia cells by tumor-promoting agents. Proc Natl Acad Sci USA. 1979;76:1293–1297
  12. Homma Y, Henning-Chubb CB, Huberman E. Translocation of protein kinase C in human leukemia cells susceptible or resistant to differentiation induced by phorbol 12-myristate 13-acetate. Proc Natl Acad Sci USA. 1986;83:7316–7319
  13. Tonetti DA, Horio M, Collart FR, Huberman E. Protein kinase C beta gene expression is associated with susceptibility of human promyelocytic leukemia cells to phorbol ester-induced differentiation. Cell Growth Differ. 1992;3:739–745
  14. Hovanessian AG. Interferon-induced and double-stranded RNA-activated enzymes: a specific protein kinase and 2′,5′-oligoadenylate synthetases. J Interferon Res. 1991;11:199–205
  15. Salzberg S, Hyman T, Turm H, Kinar Y, Schwartz Y, Nir U, et al. Ectopic expression of 2-5A synthetase in myeloid cells induces growth arrest and facilitates the appearance of a myeloid differentiation marker. Cancer Res. 1997;57:2732–2740
  16. Hyman T, Rothmann C, Heller A, Malik Z, Salzberg S. Structural characterization of erythroid and megakaryocytic differentiation in Friend erythroleukemia cells. Exp Hematol. 2001;29:563–571
  17. Gopas J, Itzhaky D, Segev Y, Salzberg S, Trink B, Isakov N, et al. Persistent measles virus infection enhances major histocompatibility complex class I expression and immunogenicity of murine neuroblastoma cells. Cancer Immunol Immunother. 1992;34:313–320
  18. Cohen B, Vaiman D, Chebath J. Enhancer functions and in vitro protein binding of native and mutated interferon-responsive sequences. Nucleic Acids Res. 1989;17:1679–1695
  19. Ihle JN, Kerr IM. JAKs and STATs in signaling by the cytokine receptor superfamily. Trends Genet. 1995;11:69–74
  20. Stark GR, Kerr IM, Williams BR, Silverman RH, Schreiber RD. How cells respond to interferons. Annu Rev Biochem. 1998;67:227–264
  21. Schafer KA. The cell cycle: a review. Vet Pathol. 1998;35:461–478
  22. Jiang H, Lin J, Su ZZ, Collart FR, Huberman E, Fisher PB. Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53. Oncogene. 1994;9:3397–3406
  23. Zeng YX, el Deiry WS. Regulation of p21WAF1/CIP1 expression by p53-independent pathways. Oncogene. 1996;12:1557–1564
  24. Tonetti DA, Henning-Chubb C, Yamanishi DT, Huberman E. Protein kinase C-beta is required for macrophage differentiation of human HL-60 leukemia cells. J Biol Chem. 1994;269:23230–23235
  25. Semizarov D, Glesne D, Laouar A, Schiebel K, Huberman E. A lineage-specific protein kinase crucial for myeloid maturation. Proc Natl Acad Sci USA. 1998;95:15412–15417
  26. Pfeffer LM, Colamonici OR. Transmembrane signalling by interferon-alpha. Pharmacol Ther. 1991;52:149–157
  27. Uddin S, Sassano A, Deb DK, Verma A, Majchrzak B, Rahman A, et al. Protein kinase C-delta (PKC-delta) is activated by type I interferons and mediates phosphorylation of STAT1 on serine 727. J Biol Chem. 2002;277:14408–14416
  28. Ivaska J, Bosca L, Parker PJ. PKCepsilon is a permissive link in integrin-dependent IFN-gamma signalling that facilitates JAK phosphorylation of STAT1. Nat Cell Biol. 2003;5:363–369
  29. Zheng X, Ravatn R, Lin Y, Shih WC, Rabson A, Strair R, et al. Gene expression of TPA induced differentiation in HL-60 cells by DNA microarray analysis. Nucleic Acids Res. 2002;30:4489–4499
  30. Tamayo P, Slonim D, Mesirov J, Zhu Q, Kitareewan S, Dmitrovsky E, et al. Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation. Proc Natl Acad Sci USA. 1999;96:2907–2912
  31. Chin YE, Kitagawa M, Su WC, You ZH, Iwamoto Y, Fu XY. Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1. Science. 1996;272:719–722
  32. Ichiba M, Miyazaki Y, Kitamura S, Kiyohara T, Shinomura Y, Matsuzawa Y. Epidermal growth factor inhibits the growth of TE8 esophageal cancer cells through the activation of STAT1. J Gastroenterol. 2002;37:497–503
  33. Benech P, Mory Y, Revel M, Chebath J. Structure of two forms of the interferon-induced (2′-5′) oligo A synthetase of human cells based on cDNAs and gene sequences. EMBO J. 1985;4:2249–2256

PII: S0145-2126(05)00062-7

doi: 10.1016/j.leukres.2005.01.015

Leukemia Research
Volume 29, Issue 8 , Pages 923-931 , August 2005