Leukemia Research
Volume 29, Issue 6 , Pages 673-677 , June 2005

A morphometric approach for the evaluation of angiogenesis in acute lymphoblastic leukemia of childhood

  • Lida Kalmanti

      Affiliations

    • Department of Medical Oncology, University Hospital of Heraklion, P.O. Box 1352, 71110 Heraklion Crete, Greece
    • ,
  • Konstantina Dampaki

      Affiliations

    • Department of Pathology, University Hospital of Heraklion, P.O. Box 1352, 71110 Heraklion Crete, Greece
    • ,
  • Helen Dimitriou

      Affiliations

    • Departments of Pediatric Hematology-Oncology, P.O. Box 1352, 71110 Heraklion Crete, Greece
    • ,
  • Eftichia Stiakaki

      Affiliations

    • Departments of Pediatric Hematology-Oncology, P.O. Box 1352, 71110 Heraklion Crete, Greece
    • ,
  • Vretos Chaniotis

      Affiliations

    • Department of Pathology, University Hospital of Heraklion, P.O. Box 1352, 71110 Heraklion Crete, Greece
    • ,
  • Efstathios Stathopoulos

      Affiliations

    • Department of Pathology, University Hospital of Heraklion, P.O. Box 1352, 71110 Heraklion Crete, Greece
    • Corresponding Author InformationCorresponding author. Tel.: +30 2810394692; fax: +30 2810394694.

Received 18 May 2004 ,Accepted 25 August 2004.

References 

  1. Keyhani A, Jendiroba DB, Freireich EJ. Angiogenesis and leukemia. Leuk Res. 2001;25:639–645
  2. Aguayo A, Kantarjian H, Manshouri T, Gidel C, Estey E, Thomas D, et al. Angiogenesis in acute and chronic leukemias and myelodysplastic syndromes. Blood. 2000;96:2240–2245
  3. Hussong JW, Rodgers GM, Shami PJ. Evidence of increased angiogenesis in patients with acute myeloid leukemia. Blood. 2000;95:309–313
  4. Perez-Atayde A, Sallan SE, Tedrow U, Connors S, Allred E, Folkman J. Spectrum of tumor angiogenesis in the bone marrow of children with acute lymphoblastic leukemia. Am J Pathol. 1997;150:815–821
  5. Aguayo A, Estey E, Kantarjian H, Mansouri T, Gidel C, Keating M, et al. Cellular vascular endothelial growth factor is a predictor of outcome in patients with acute myeloid leukemia. Blood. 1999;94:3717–3721
  6. Vermeulen PB, Gasparini G, Fox SB, Toi M, Martin L, McCulloch P, et al. Quantification of angiogenesis in solid tumors: an international consensus on the methodology and criteria of evaluation. Eur J Cancer. 1996;14:2474–2484
  7. Protopapa E, Delides GS, Revesz L. Vascular density and the response of breast carcinomas to mastectomy and adjuvant chemotherapy. Eur J Cancer. 1993;29A:1391–1393
  8. Pule MA, Gullmann C, Dennis D, McMahon C, Jeffers M, Smith OP. Increased angiogenesis in bone marrow of children with acute lymphoblastic leukemia has no prognostic significance. Br J Haematol. 2002;118:991–998
  9. Padró T, Ruiz S, Bieker R, Burger H, Steins M, Kienast J, et al. Increased angiogenesis in the bone marrow of patients with acute myeloid leukemia. Blood. 2000;95:2637–2644
  10. Weidner N, Semple JP, Welch WR, Folkman J. Tumor angiogenesis and metastasis: correlation in invasive breast carcinoma. N Eng J Med. 1991;324:1–8
  11. Elias H, Hyde DM. Stereological measurements of isotropic structures. In:  Elias H,  Hyde DM editor. A guide to practical stereology. Basel: S. Karger; 1983;p. 25
  12. Haapasalo H, Collan Y, Pesonen E. Volume-corrected mitotic index (M/V index) the standard of mitotic activity in neoplasms. Pathol Res Pract. 1989;185:551–554
  13. Delesse A. Procede mechanique pour determines la composition des roches (extrait). C R Academy of Science (Paris) 1847;25:544 [cited by Aherne WA, Dunnill MS. Morphometry. London: E Arnold, publ, 1982: p. 33–45].
  14. Moehler TM, Ho AD, Goldschmidt H, Barlogie B. Angiogenesis in hematologic malignancies. Crit Rev Oncol Hematol. 2003;45:227–244
  15. Yetgin S, Yenicesu I, Cetin M, Tuncer M. Clinical importance of serum vascular endothelial and basic fibroblast growth factors in children with acute lymphoblastic leukemia. Leuk Lymphoma. 2001;42:83–88

PII: S0145-2126(05)00036-6

doi: 10.1016/j.leukres.2004.08.013

Leukemia Research
Volume 29, Issue 6 , Pages 673-677 , June 2005

Article Tools

* Image Usage & Resolution