Leukemia Research
Volume 28, Issue 12 , Pages 1341-1345 , December 2004

The p73 locus is commonly deleted in non-Hodgkin’s lymphomas

  • Archontoula Stoffel

      Affiliations

    • Laboratory for Cancer Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 212 327 7057; fax: +1 212 327 7058.
    • ,
  • Daniel Filippa

      Affiliations

    • Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    • ,
  • Pulivarthi H. Rao

      Affiliations

    • Laboratory of Molecular Cytogenetics, Texas Children’s Cancer Center, Baylor College of Medicine, 6621 Fannin Street, MC 3-3320, Houston, TX 77030, USA
    • Co-corresponding author. Tel.: +1 832 824 4820; fax: +1 832 825 4846.

Received 28 January 2004 ,Accepted 21 April 2004.

References 

  1. Herranz M, Urioste M, Santos J, Rivas C, Martinez B, Benitez J, et al  Analysis of the INK4a/ARF locus in non-Hodgkin’s lymphomas using two new internal microsatellite markers. Leukemia. 1999;13:808–810
  2. Dave BJ, Hess MM, Pickering DL, Zaleski DH, Pfeifer AL, Weisenburger DD, et al.  Rearrangements of chromosome band 1p36 in non-Hodgkin’s lymphoma. Clin. Cancer Res. 1999;5:1401–1409
  3. Kaghad M, Bonnet H, Yang A, Creancier L, Biscan J-C, Valent A, et al.  Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in Neuroblastoma and other human cancers. Cell. 1997;90:809–819
  4. Corn PG, Kuerbitz SJ, van Noesel MM, Esteller M, Compitello N, Baylin SB, et al.  Transcriptional silencing of the p73 gene in acute lymphoblastic leukemia and Burkitt’s lymphoma is associated with 5′ CpG island methylation. Cancer Res. 1999;59:3352–3356
  5. Kawano S, Miller CW, Gombart AF, Bartram CR, Matsuo Y, Asou H, et al.  Loss of p73 expression in leukemias/lymphomas due to hypermethylation. Blood. 1999;94:1113–1120
  6. Ahomadegbe JC, Tourpin S, Kaghad M, Zelek L, Vayssade M, Mathieu MC, et al.  Loss of heterozygosity, allele silencing and decreased expression of p73 gene in breast cancers: prevalence of alterations in inflammatory breast cancers. Oncogene. 2000 5413-L 5418;19:
  7. Marin MC, Jost CA, Irwin MS, DeCaprio JA, Caput D, Kaelin WG. Viral oncoproteins discriminate between p53 and the p53 homolog p73. Mol. Cell. Biol. 1998;18:6316–6324
  8. Herranz M, Urioste M, Santos J, Martinez-Delgado JB, Rivas C, Benitez J, et al.  Allelic losses and genetic instabilities of PTEN and p73 in non-Hodgkin lymphomas. Leukemia. 2000;14:1325–1327

PII: S0145-2126(04)00178-X

doi: 10.1016/j.leukres.2004.04.010

Leukemia Research
Volume 28, Issue 12 , Pages 1341-1345 , December 2004

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