Leukemia Research
Volume 28, Issue 12 , Pages 1263-1265, December 2004

Alcohol intake and incidence of de novo adult acute leukemia

  • Garth H. Rauscher

      Affiliations

    • School of Public Health, Division of Epidemiology and Biostatistics, University of Illinois at Chicago, 816 SPHPI (M/C 923), 1603 W. Taylor, Chicago, IL 60612, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 312 413 4317; fax: +1 312 996 0064.
  • ,
  • David Shore

      Affiliations

    • National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
  • ,
  • Dale P. Sandler

      Affiliations

    • National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA

Received 14 January 2004; accepted 5 April 2004.

Abstract 

In a case-control study of adult acute leukemia we defined alcohol intake as either non-regular (<1 drink per week), light (1–5 drinks per week), moderate (6–8 drinks per week) or heavy (>8 drinks per week). An inverse association was found for light and moderate beer intake (RR = 0.58; 95% CI: 0.44, 0.76). In contrast, a positive association was found for moderate and heavy wine intake (RR = 2.1; 95% CI: 1.2, 3.8). Divergent results might reflect the effect of different nutrients in beer and wine, unmeasured confounding, or differing impacts of selection bias on these associations.

Keywords:  Leukemia, Alcohol, Case-control study, Bias

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PII: S0145-2126(04)00129-8

doi:10.1016/j.leukres.2004.04.004

Leukemia Research
Volume 28, Issue 12 , Pages 1263-1265, December 2004