Next »
Leukemia Research
Volume 28, Issue 12
, Pages 1303-1312
, December 2004
Induction of anti-leukemic cytotoxic T lymphocytes by fusion of patient-derived dendritic cells with autologous myeloblasts
References
- . Cancer immunotherapy. Can Med. Assoc. J. 1979;120:322–324
- . Active specific immunotherapy of murine leukemia. Part I. Irradiated tumor cell vaccine. Int. J. Cancer. 1979;24:629–635
- . Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes. J. Exp. Med. 1995;182:255–260
- . Primary stimulation by dendritic cells induces antiviral proliferative and cytotoxic T cell responses in vitro. J. Exp. Med. 1989;169:1255–1264
- . Influenza virus-infected dendritic cells stimulate strong proliferative and cytolytic responses from human CD8+ T cells. J. Clin Invest. 1994;94:797–807
- . Development of dendritic cells and their use in tumor therapy. Clin Immunol. 1999;92:119–127
- The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro. J. Exp. Med. 1994;180:1849–1860
- . Dendritic cells in cancer immunotherapy. Annu. Rev. Immunol. 2000;18:245–273
- . The B7/BB1 antigen provides one of several costimulatory signals for the activation of CD4+ T lymphocytes by human blood dendritic cells in vitro. J. Clin Invest. 1992;90:229–237
- . Identification of a malignant counterpart of the monocyte-dendritic cell progenitor in an acute myeloid leukemia. Blood. 1994;84:3054–3062
- . CD34(+) acute myeloid and lymphoid leukemic blasts can be induced to differentiate into dendritic cells. Blood. 1999;94:2048–2055
- Dendritic cells derived in vitro from acute myelogenous leukemia cells stimulate autologous, antileukemic T-cell responses. Blood. 1999;93:780–786
- . Human leukemia-derived dendritic cells: ex-vivo development of specific antileukemic cytotoxicity. Crit. Rev. Immunol. 1998;18:121–131
- . Human acute myeloblastic leukemia cells differentiate in vitro into mature dendritic cells and induce the differentiation of cytotoxic T cells against autologous leukemias. Eur. J. Immunol. 1999;29:2567–2578
- Induction of leukemia-specific cytotoxic response by cross-presentation of late-apoptotic leukemic blasts by autologous dendritic cells of nonleukemic origin. Cancer Res. 2002;62:2861–2868
- . The causes of acute leukemia. Curr. Opin. Oncol. 1999;11:20–24
- . Acute myeloid leukemia. N Engl. J. Med. 1999;341:1051–1062
- . Active immunization against cancer with dendritic cells: the near future. Int. J. Cancer. 2001;94:459–473
- Cancer therapy using a self-replicating RNA vaccine. Nat. Med. 1999;5:823–827
- . Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA. Nat. Biotechnol. 1998;16:364–369
- . Induction of anti-tumor immunity by vaccination of dendritic cells transfected with MUC1 RNA. J. Immunol. 2000;165:5713–5719
- . In vitro-synthesized infectious RNA as an attenuated live vaccine in a flavivirus model. Nat Med. 1998;4:1438–1440
- . Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo. J. Exp. Med. 1996;184:465–472
- . Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity. J. Exp. Med. 1996;183:283–287
- Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity. Nat Med. 1995;1:1297–1302
- . Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo. J. Exp. Med. 1996;183:317–322
- . Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells. Nat. Med. 1998;4:328–332
- . Dendritic cells acquire antigen from apoptotic cells and induce class I—restricted CTLs. Nature. 1998;392:86–89
- . Induction of anti-tumor activity by immunization with fusions of dendritic and carcinoma cells. Nat. Med. 1997;3:558–561
-
Reversal of tolerance to human MUC1 antigen in MUC1 transgenic mice immunized with fusions of dendritic and carcinoma cells.
Proc. Natl. Acad. Sci. U.S.A. 1998;95:6279–6283
- . Physical interaction between dendritic cells and tumor cells results in an immunogen that induces protective and therapeutic tumor rejection. J. Immunol. 1998;160:3081–3085
- Dendritic cells fused with mastocytoma cells elicit therapeutic anti-tumor immunity. Int. J. Cancer. 1998;76:250–258
- . Eliciting T cell immunity against poorly immunogenic tumors by immunization with dendritic cell-tumor fusion vaccines. J. Immunol. 1998;161:5516–5524
- . Antitumor Effect of Immunizations With Fusions of Dendritic and Glioma Cells in a Mouse Brain Tumor Model. J. Immunother. 2001;24:106–113
- . Preventive anti-tumor activity against hepatocellular carcinoma (HCC) induced by immunization with fusions of dendritic cells and HCC cells in mice. J. Gastroenterol. 2001;36:764–771
- . Results of a phase I clinical trial of vaccination of glioma patients with fusions of dendritic and glioma cells. Cancer Immunol. Immunother. 2001;50:337–344
-
Activation of anti-tumor cytotoxic T lymphocytes by fusions of human dendritic cells and breast carcinoma cells.
Proc. Natl. Acad. Sci. U.S.A. 2000;97:2715–2718
- Fusions of human ovarian carcinoma cells with autologous or allogeneic dendritic cells induce anti-tumor immunity. J. Immunol. 2000;165:1705–1711
- Hybrid cell vaccination for cancer immune therapy: first clinical trial with metastatic melanoma. Int. J. Cancer. 2000;85:618–626
- . Eliciting cytotoxic T lymphocytes against acute myeloid leukemia-derived antigens: evaluation of dendritic cell-leukemia cell hybrids and other antigen-loading strategies for dendritic cell-based vaccination. Cancer Immunol. Immunother. 2002;51:299–310
- . The kinetics of in vivo priming of CD4 and CD8 T cells by dendritic/tumor fusion cells in MUC1-transgenic mice. J. Immunol. 2002;168:2111–2117
- . Engineered fusion hybrid vaccine of IL-4 gene-modified myeloma and relative mature dendritic cells enhances anti-tumor immunity. Leuk. Res. 2002;26:757–763
- A new genetic method to generate and isolate small, short-lived but highly potent dendritic cell-tumor cell hybrid vaccines. Nat. Med. 2003;9:1215–1219
- . Immature dendritic cell/tumor cell fusions induce potent antitumour immunity. Eur. J. Clin Invest. 2003;33:897–904
- Mediators of innate immunity that target immature, but not mature, dendritic cells induce anti-tumor immunity when genetically fused with nonimmunogenic tumor antigens. J. Immunol. 2001;167:6644–6653
PII: S0145-2126(04)00125-0
doi: 10.1016/j.leukres.2004.03.018
© 2004 Elsevier Ltd. All rights reserved.
Next »
Leukemia Research
Volume 28, Issue 12
, Pages 1303-1312
, December 2004
