Leukemia Research
Volume 28, Issue 10 , Pages 1053-1055 , October 2004

An association study of the tumor necrosis factor alpha C-850T polymorphism and childhood acute lymphoblastic leukemia in a population from northern Greece

  • Liana Fidani

      Affiliations

    • Department of General Biology, Medical Faculty, Aristotle University of Thessaloniki, GR-54124, Thessaloniki, Greece
    • Corresponding Author InformationCorresponding author. Tel.: +30-2310-280475; fax: +30-2310-999303.
    • ,
  • Fani Athanassiadou-Piperopoulou

      Affiliations

    • Second Pediatric University Clinic, AHEPA Hospital, GR-54124, Thessaloniki, Greece
    • ,
  • Antonis Goulas

      Affiliations

    • Department of Experimental Pharmacology, Medical Faculty, Aristotle University of Thessaloniki, GR-54124, Thessaloniki, Greece
    • ,
  • Konstantinos Chatzidakis

      Affiliations

    • Department of Experimental Pharmacology, Medical Faculty, Aristotle University of Thessaloniki, GR-54124, Thessaloniki, Greece
    • ,
  • Dimitrios Koliouskas

      Affiliations

    • Department of Pediatric Oncology, Hippokration Hospital, GR-54642, Thessaloniki, Greece
    • ,
  • Alexandros Kotsis

      Affiliations

    • Department of General Biology, Medical Faculty, Aristotle University of Thessaloniki, GR-54124, Thessaloniki, Greece

Received 16 October 2003 ,Accepted 19 January 2004.

References 

  1. Hajeer AH, Hutchinson IV. Influence of TNFα gene polymorphisms on TNFalpha production and disease. Hum. Immunol. 2001;62:1191–1199
  2. Warzocha K, Ribeiro P, Bienvenue I, et al.  Genetic polymorphisms in the tumor necrosis factor locus influence non-Hodgkin’s lymphoma outcome. Blood. 1998;91:3574–3581
  3. Saarinen UM, Koskelo EK, Teppo AM, Siimes MA. Tumor necrosis factor in children with malignancies. Cancer Res. 1990;50:592–595
  4. Ishii E, Ohga S, Ueda K, Akazawa K. Serum interleukin-1 and tumor necrosis factor activities in febrile children with acute leukemia. Int. J. Hematol. 1991;54:79–84
  5. Takeuchi S, Takeuchi N, Tsukasaki K, et al.  Genetic polymorphisms in the tumour necrosis factor locus in childhood acute lymphoblastic leukaemia. Br. J. Haematol. 2002;119:985–987
  6. Kato T, Honda M, Kuwata S, et al.  Novel polymorphism in the promoter region of the tumor necrosis factor alpha gene: no association with narcolepsy. Am. J. Med. Genet. 1999;88:301–304
  7. Tsukasaki K, Miller CW, Kubota T, et al.  Tumor necrosis factor α polymorphism associated with increased susceptibility to development of adult T-cell leukemia/lymphoma in human T-lymphotropic virus type 1 carriers. Cancer Res. 2001;61:3770–3774
  8. McCusker SM, Curran MD, Dynan KB, et al.  Association between polymorphism in regulatory region of gene encoding tumour necrosis factor α and risk of Alzheimer’s disease and vascular dementia: a case-control study. Lancet. 2001;357:436–439
  9. Lauten M, Matthias T, Stanulla M, et al.  Association of initial response to prednisone treatment in childhood acute lymphoblastic leukemia and polymorphisms within the tumour necrosis factor and the interleukin-10 genes. Leukemia. 2002;16:1437–1442
  10. Infante J, Llorca J, Berciano J, Combarros O. No synergistic effect between -850 tumor necrosis factor-α promoter polymorphism and apolipoprotein E ε4 allele in Alzheimer’s disease. Neurosci. Lett. 2002;328:71–73
  11. Terreni L, Fogliarino S, Quadri P, et al.  Tumor necrosis factor polymorphism C-850T is not associated with Alzheimer’s disease and vascular dementia in an Italian population. Neurosci. Lett. 2003;344:135–137

PII: S0145-2126(04)00062-1

doi: 10.1016/j.leukres.2004.01.018

Leukemia Research
Volume 28, Issue 10 , Pages 1053-1055 , October 2004

Article Tools