Leukemia Research
Volume 28, Issue 3 , Pages 217-218 , March 2004

Tyrosine kinases in AML: where do they fit in?

References 

  1. Blume-Jensen P, Hunter T. Oncogenic kinase signalling. Nature. 2001;411:355
  2. Castilla LH, Garrett L, Adya N, Orlic D, Dutra A, Anderson S, et al.  The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia. Nat. Genet. 1999;23:144
  3. Wiemels JL, Ford AM, Van Wering ER, Postma A, Greaves M. Protracted and variable latency of acute lymphoblastic leukemia after TEL-AML1 gene fusion in utero. Blood. 1999;94:1057
  4. Birg F, Courcoul M, Rosnet O, Bardin F, Pebusque MJ, Marchetto S, et al.  Expression of the FMS/KIT-like gene FLT3 in human acute leukemias of the myeloid and lymphoid lineages. Blood. 1992;80:2584
  5. Nakao M, Yokota S, Iwai T, Kaneko H, Horiike S, Kashima K, et al.  Internal tandem duplication of the flt3 gene found in acute myeloid leukemia. Leukemia. 1996;10:1911
  6. Kiyoi H, Towatari M, Yokota S, Hamaguchi M, Ohno R, Saito H, et al.  Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product. Leukemia. 1998;12:1333
  7. Gilliland DG, Griffin JD. The roles of FLT3 in hematopoiesis and leukemia. Blood. 2002;100:1532
  8. Yamamoto Y, Kiyoi H, Nakano Y, Suzuki R, Kodera Y, Miyawaki S, et al.  Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies. Blood. 2001;97:2434
  9. Abu-Duhier FM, Goodeve AC, Wilson GA, Care RS, Peake IR, Reilly JT. Identification of novel FLT-3 Asp835 mutations in adult acute myeloid leukaemia. Br. J. Haematol. 2001;113:983
  10. Zheng R, Klang K, Gorin NC, Small D. Lack of Kit or FMS internal tandem duplications but co-expression with ligands in AML. Leuk Res.
  11. Dubreuil P, Torres H, Courcoul MA, Birg F, Mannoni P. c-fms expression is a molecular marker of human acute myeloid leukemias. Blood. 1988;72:1081
  12. Rambaldi A, Wakamiya N, Vellenga E, Horiguchi J, Warren MK, Kufe D, et al.  Expression of the macrophage colony-stimulating factor and c-fms genes in human acute myeloblastic leukemia cells. J. Clin. Invest. 1988;81:1030
  13. Wang C, Curtis JE, Geissler EN, McCulloch EA, Minden MD. The expression of the proto-oncogene C-kit in the blast cells of acute myeloblastic leukemia. Leukemia. 1989;3:699
  14. Ikeda H, Kanakura Y, Tamaki T, Kuriu A, Kitayama H, Ishikawa J, et al.  Expression and functional role of the proto-oncogene c-kit in acute myeloblastic leukemia cells. Blood. 1991;78:2962
  15. Kelly LM, Liu Q, Kutok JL, Williams IR, Boulton CL, Gilliland DG. FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model. Blood. 2002;99:310
  16. Deguchi K, Gilliland DG. Cooperativity between mutations in tyrosine kinases and in hematopoietic transcription factors in AML. Leukemia. 2002;16:740
  17. Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S. The protein kinase complement of the human genome. Science. 2002;298:1912
  18. Bardelli A, Parsons DW, Silliman N, Ptak J, Szabo S, Saha S, et al.  Mutational analysis of the tyrosine kinome in colorectal cancers. Science. 2003;300:949

PII: S0145-2126(03)00268-6

doi: 10.1016/j.leukres.2003.07.003

Leukemia Research
Volume 28, Issue 3 , Pages 217-218 , March 2004