Leukemia Research
Volume 27, Issue 6 , Pages 493-498 , June 2003

High tumor necrosis factor-α levels in the patients with Epstein–Barr virus-associated peripheral T-cell proliferative disease/lymphoma

  • Atsumi Mori

      Affiliations

    • Department of Biological Sciences, School of Science, University of Tokyo, Hongo, Bunkyo-ku, Tokyo, 113-0033 Japan
  • ,
  • Satomi Takao

      Affiliations

    • Department of Biological Sciences, School of Science, University of Tokyo, Hongo, Bunkyo-ku, Tokyo, 113-0033 Japan
  • ,
  • Jintana Pradutkanchana

      Affiliations

    • Department of Pathology, Faculty of Medicine, Prince of Songkla University, Hat Yai, 90110 Thailand
  • ,
  • Suparp Kietthubthew

      Affiliations

    • Department of Stomatology, Faculty of Dentistry, Prince of Songkla University, Hat Yai, 90110 Thailand
  • ,
  • Winyou Mitarnun

      Affiliations

    • Department of Pathology, Faculty of Medicine, Prince of Songkla University, Hat Yai, 90110 Thailand
  • ,
  • Takafumi Ishida

      Affiliations

    • Department of Biological Sciences, School of Science, University of Tokyo, Hongo, Bunkyo-ku, Tokyo, 113-0033 Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81-3-5841-4633; fax: +81-3-3818-7547.

Received 11 June 2002 ,Accepted 11 October 2002.

References 

  1. Su I, Hsieh H, Lin K, Uen W, Kao C, Chen C, et al.  Aggressive peripheral T-cell lymphomas containing Epstein–Barr viral DNA: a clinicopathologic and molecular analysis. Blood. 1991;77:799–808
  2. Anagnostopoulos I, Hummel M, Stein H. Frequent presence of latent Epstein–Barr virus infection in peripheral T-cell lymphomas. A review. Leuk. Lymphoma. 1995;19:1–12
  3. Mitarnun W, Kietthubthew S, Suwiwat S. Hepatic peripheral T-cell lymphoma: a spectrum of liver pathology and clinical correlation. J. Med. Assoc. Thai. 1997;80:219–232
  4. Mitarnun W, Suwiwat S, Pradutkanchana J, Saechan V, Ishida T, Takao S, et al.  Epstein–Barr virus-associated peripheral T-cell and NK-cell proliferative disease/lymphoma: a clinicopathologic, serologic and molecular analysis. Am. J. Hematol. 2002;70:31–38
  5. Kaye KM, Izumi KM, Mosialos G, Kieff E. The Epstein–Barr virus LMP1 cytoplasmic carboxy terminus is essential for B-lymphocyte transformation; fibroblast cocultivation complements a critical function within the terminal 155 residues. J. Virol. 1995;69:675–683
  6. Liebowitz D. Epstein–Barr virus and a cellular signaling pathway in lymphomas from immunosuppressed patients. N. Engl. J. Med. 1998;338:1413–1421
  7. Matthews N. Tumor necrosis factor from the rabbit V. Synthesis in vitro by mononuclear phagocytes from various tissues of normal and BCG-injected rabbits. Br. J. Cancer. 1981;44:418–424
  8. Saarinen UM, Koskelo EK, Teppo AM, Siimes MA. Tumor necrosis factor in children with malignancies. Cancer Res. 1990;50:592–595
  9. Raziuddin S, Sheikha A, Abu-Eshy S, Al-Janadi M. Circulating levels of cytokines and soluble cytokine receptors in various T-cell malignancies. Cancer. 1994;73:2426–2431
  10. Lay JD, Tsao CJ, Chen JY, Kadin ME, Su IJ. Upregulation of tumor necrosis factor-alpha gene by Epstein–Barr virus and activation of macrophages in Epstein–Barr virus-infected T-cells in the pathogenesis of hemophagocytic syndrome. J. Clin. Invest. 1997;100:1969–1979
  11. Foss HD, Anagnostopoulos I, Herbst H, Grebe M, Ziemann K, Hummel M, et al.  Patterns of cytokine gene expression in peripheral T-cell lymphoma of angioimmunoblastic lymphadenopathy type. Blood. 1995;85:2862–2869
  12. Ross ME, Caligiuri MA. Cytokine-induced apoptosis of human natural killer cells identifies a novel mechanism to regulate the innate immune response. Blood. 1997;89:910–918
  13. Xu J, Ahmad A, Menezes J. Preferential localization of the Epstein–Barr virus (EBV) oncoprotein LMP-1 to nuclei in human T-cells: implications for its role in the development to EBV genome-positive T-cell lymphomas. J. Virol. 2002;76:4080–4086
  14. Barak V, Nisman B, Polliack A. The tumor necrosis factor family and correlation with disease activity and response to treatment in hairy cell leukemia. Eur. J. Haematol. 1999;62:71–75
  15. Wilson AG, Symons JA, McDowell TL, McDevitt HO, Duff GW. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc. Natl. Acad. Sci. U.S.A. 1997;94:3195–3199
  16. Louis E, Franchimont D, Piron A, Gevaert Y, Schaaf-Lafontaine N, Roland S, et al.  Tumor necrosis factor (TNF) gene polymorphism influences TNF-α production in lipopolysaccharide (LPS)-stimulated whole blood cell culture in healthy humans. Clin. Exp. Immunol. 1998;113:401–406
  17. Skoog T, van’t Hooft FM, Kallin B, Jovinge S, Boquist S, Nilsson J, et al.  A common functional polymorphism (C→A substitution at position −863) in the promoter region of the tumour necrosis factor-α (TNF-α) gene associated with reduced circulating levels of TNF-α. Hum. Mol. Genet. 1999;8:1443–1449

PII: S0145-2126(02)00266-7

doi: 10.1016/S0145-2126(02)00266-7

Leukemia Research
Volume 27, Issue 6 , Pages 493-498 , June 2003