Leukemia Research
Volume 27, Issue 1 , Pages 93-94 , January 2003

A polymorphism in the angiogenesis inhibitor, endostatin, in multiple myeloma

  • Manoela M Ortega

      Affiliations

    • Department of Internal Medicine, State University of Campinas, Campinas, São Paulo, Brazil
    • ,
  • Helvia Nascimento

      Affiliations

    • Department of Internal Medicine, State University of Campinas, Campinas, São Paulo, Brazil
    • ,
  • Maria T Teori

      Affiliations

    • Haematology and Haemotherapy Centre, State University of Campinas, Cidade Universitária “Zeferino Vaz”, Campinas, São Paulo, Brazil CP: 6198, Cep 13081-970
    • ,
  • Fernando F Costa

      Affiliations

    • Department of Internal Medicine, State University of Campinas, Campinas, São Paulo, Brazil
    • ,
  • Carmen S.P Lima

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +55-19-3788-8729; fax: +55-19-3788-8600.
    • Haematology and Haemotherapy Centre, State University of Campinas, Cidade Universitária “Zeferino Vaz”, Campinas, São Paulo, Brazil CP: 6198, Cep 13081-970

References 

  1. Gupta D, Treon SP, Shima Y, Hideshima T, Podar K, Tai Y, et al.  Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applications. Leukemia. 2001;15:1950–1961
  2. Vacca A, Ribatti D, Roncali L, Ranieri G, Serio G, Silvestris F, et al.  Bone marrow angiogenesis and progression in multiple myeloma. Br. J. Haematol. 1994;87:503–508
  3. Guenther U, Herbst H, Bauer M, Isbert C, Buhr HJ, Riecken EO, et al.  Collagen type XVIII/endostatin is differentially expressed in primary and metastatic colorectal cancers and ovarian carcinomas. Br. J. Cancer. 2001;85:1540–1545
  4. Scappaticci FA, Smith R, Pathak A, Schloss D, Lum B, Cao Y, et al.  Combination angiostatin and endostatin gene transfer induces synergistic antiangiogenic activity in vitro and antitumor efficacy in leukemia and solid tumors in mice. Mol. Ther. 2001;3:186–196
  5. Zorick TS, Mustacchi Z, Bando SY, Zatz M, Moreira-Filho CA, Olsen B, et al.  High serum endostatin levels in Down syndrome: implications for improved treatment and prevention of solid tumors. Eur. J. Hum. Genet. 2001;9:811–814
  6. Iughetti P, Suzuki O, Godoi PHC, Alves VAF, Sertie AL, Zorick T, et al.  A polymorphism in endostatin, an angiogenesis inhibitor, predisposes for the development of prostatic adenocarcinoma. Cancer Res. 2001;61:7375–7378

PII: S0145-2126(02)00218-7

Leukemia Research
Volume 27, Issue 1 , Pages 93-94 , January 2003

Article Tools

* Image Usage & Resolution