Leukemia Research
Volume 26, Issue 11 , Pages 1035-1041 , November 2002

Relationships of in vitro sensitivities tested with nine drugs and two types of irradiation in chronic lymphocytic leukemia

  • Ilkka Kivekäs

      Affiliations

    • Laboratory of Molecular Hematology, Department of Clinical Chemistry, Laboratory Center of Tampere University Hospital, P.O. Box 2000, Tampere, FIN 33521, Finland
    • Department of Medicine, Tampere University Medical School, P.O. Box 2000, Tampere, FIN 33521, Finland
    • ,
  • Leena Vilpo

      Affiliations

    • Laboratory of Molecular Hematology, Department of Clinical Chemistry, Laboratory Center of Tampere University Hospital, P.O. Box 2000, Tampere, FIN 33521, Finland
    • Department of Medicine, Tampere University Medical School, P.O. Box 2000, Tampere, FIN 33521, Finland
    • ,
  • Juhani Vilpo

      Affiliations

    • Laboratory of Molecular Hematology, Department of Clinical Chemistry, Laboratory Center of Tampere University Hospital, P.O. Box 2000, Tampere, FIN 33521, Finland
    • Department of Medicine, Tampere University Medical School, P.O. Box 2000, Tampere, FIN 33521, Finland
    • Corresponding Author InformationCorresponding author. Tel.: +358-3-247-5290; fax: +358-3-247-4048.

Received 20 November 2001 ,Accepted 26 February 2002.

References 

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  2. Bosanquet AG, Bell PB. Novel ex vivo analysis of nonclassical, pleiotropic drug resistance and collateral sensitivity induced by therapy provides a rationale for treatment strategies in chronic lymphocytic leukemia. Blood. 1996;87:1962–1971
  3. Myllyperkiö M, Koski T, Vilpo L, Vilpo J. Gamma-irradiation-induced DNA single- and double-strand breaks and their repair in chronic lymphocytic leukemia of variable radiosensitivity. Hematol. Cell Therapy. 1999;41:95–103
  4. Myllyperkiö M, Koski T, Vilpo L, Vilpo J. Kinetics of excision repair of UV-induced DNA damage, measured using the comet assay. Mutat. Res. 1999;448:1–9
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  10. Koski T, Karhu R, Visakorpi T, Vilpo L, Knuutila S, Vilpo J. Complex chromosomal aberrations in chronic lymphocytic leukemia are associated with cellular drug and irradiation resistance. Eur. J. Haematol. 2000;65:32–39
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PII: S0145-2126(02)00050-4

Leukemia Research
Volume 26, Issue 11 , Pages 1035-1041 , November 2002

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