Leukemia Research
Volume 26, Issue 10 , Pages 899-902 , October 2002

Less apoptosis in patients with 5q-syndrome than in patients with refractory anemia

Received 10 August 2001 ,Accepted 5 February 2002.

References 

  1. Harris NL, Jaffe ES, Diebold J, Flandrin G, Muller-Hermelink HK, Vardiman, J, et al. In: Proceedings of The World Health Organization classification of hematological malignancies report of the Clinical Advisory Committee Meeting. Airlie House, VA, November 1997. Mod. Pathol. 2000;13:193–207.
  2. Van den Berghe H, Vermaelen K, Mecucci C, Barbieri D, Tricot G. The 5q-anomaly. Cancer Genet. Cytogenet. 1985;17:189–255
  3. Teerenhovi L. Specificity of haematological indicators for 5q-syndrome in patients with myelodysplastic syndromes. Euro J. Haemat. 1987;39:326–330
  4. Washington LT, Doherty D, Glassman A, Martins J, Ibrahim S, Lai R. 5q as a sole chromosome abnormality in myelodysplastic syndromes and acute myeloid leukemia (Abstract). Mod. Pathol. 2001;14:182A
  5. Raza A, Alvi S, Borok RZ, et al.  Excessive proliferation matched by excessive apoptosis in myelodysplastic syndromes: the cause–effect relationship. Leuk. Lymphoma. 1997;27:111–118
  6. Merchant SH, Gonchoroff NJ, Hutchison RE. Apoptotic index by annexin V flow cytometry: adjunct to morphologic and cytogenetic diagnosis of myelodysplastic syndromes. Cytometry. 2001;46:28–32
  7. Cossarizza A, Baccarani-Contri M, Kalashnikova G, Franceschi C. A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolcarbocyanine iodide (JC-1). Biochem. Biophys. Res. Commun. 1993;197:40–45
  8. Katz E, Deehan MR, Seatter S, Lord C, Sturrock RD, Harnett MM. B cell receptor-stimulated mitochondrial phospholipase A2 activation and resultant disruption of mitochondrial membrane potential correlate with the induction of apoptosis in WEHI-231 B cells. J. Immunol. 2001;166:137–147
  9. Cossarizza A, Baccarani-Contri M, Kalashnikova G, Franceschi C. A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolcarbocyanine iodide (JC-1). Biochem. Biophys. Res. Commun. 1993;197(1):40–45

PII: S0145-2126(02)00039-5

Leukemia Research
Volume 26, Issue 10 , Pages 899-902 , October 2002

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