Leukemia Research
Volume 26, Issue 11 , Pages 1047-1049 , November 2002

Two different karyotypes with 1q abnormalities in a patient with Fanconi anemia

  • Neide I.S.S Oliveira

      Affiliations

    • Laboratório de Citogenética Humana, Departamento de Genética, Universidade Federal do Paraná (UFPR), Caixa Postal 19071, CEP 81531-970, Curitiba, Paraná, Brazil
    • ,
  • Enilze M.S.F Ribeiro

      Affiliations

    • Laboratório de Citogenética Humana, Departamento de Genética, Universidade Federal do Paraná (UFPR), Caixa Postal 19071, CEP 81531-970, Curitiba, Paraná, Brazil
    • ,
  • Susana C Raimondi

      Affiliations

    • Cytogenetics Laboratory, Department of Pathology, St. Jude Children’s Research Hospital, Memphis, TN, USA
    • ,
  • Marco A Bittencourt

      Affiliations

    • Serviço de Transplante de Medula Óssea, Hospital de Clı́nicas, UFPR, Curitiba, Paraná, Brazil
    • ,
  • Ricardo Pasquini

      Affiliations

    • Serviço de Transplante de Medula Óssea, Hospital de Clı́nicas, UFPR, Curitiba, Paraná, Brazil
    • ,
  • Iglenir J Cavalli

      Affiliations

    • Laboratório de Citogenética Humana, Departamento de Genética, Universidade Federal do Paraná (UFPR), Caixa Postal 19071, CEP 81531-970, Curitiba, Paraná, Brazil
    • Corresponding Author InformationCorresponding author. Tel.: +55-41-266-2042; fax: +55-41-266-2042.

Received 23 October 2001 ,Accepted 6 February 2002.

References 

  1. Fanconi G. Familial constitutional panmyelocytopathy. Fanconi’s anemia (FA). I. Clinical aspects. Semin. Hematol. 1967;4:233–240
  2. Swift MR. Fanconi’s anaemia in the genetics of neoplasia. Nature. 1971;230:370–373
  3. Schroeder TM, Tilgen D, Kruger J, Vogel F. Formal genetics of Fanconi’s anemia. Hum. Genet. 1976;32:257–288
  4. Joenje H, Patel KJ. The emerging genetic and molecular basis of Fanconi anemia. Nature Rev. Genet. 2001;2:446–459
  5. Alter BP, Caruso JP, Drachtman RA, et al.  Fanconi anemia: myelodysplasia as a predictor of outcome. Cancer Genet. Cytogenet. 2000;117:125–131
  6. Raimondi SC, Mathew S, Pui C-H. Cytogenetics as a diagnostic aid for childhood hematologic disorders. In: Hanausek M, Walaszek Z, editors. Methods in molecular medicine, tumor markers protocols, vol. 14. Totowa, NJ: Humanae Press, 1998. p. 209–27.
  7. Mitelman F, editor. ISCN, an international system for human cytogenetic nomenclature. Basel: S. Karger, 1995.
  8. Carbone P, Barbata G, Mirto S, Granata G. Inherited aplastic anemia with abnormal clones in bone marrow and increased endoreduplication in peripheral lymphocytes. Cancer Genet. Cytogenet. 1984;13:259–266
  9. Maarek O, Jonveaux P, Le Coniat M, et al.  Fanconi anemia and bone marrow clonal chromosome abnormalities. Leukemia. 1996;10:1700–1704
  10. Babu Rao V, Kerketta L, Ghosh K, Mohanty DA. 46,XY,dup(1)(q21q32), add(11)(q23) karyotype in a case of Fanconi anemia. Leuk. Res. 2001;25:347–348
  11. Fundia A, Gorla N, Larripa I. Spontaneous chromosome aberrations in Fanconi’s anemia patients are located at fragile sites and acute myeloid leukemia breakpoints. Hereditas. 1994;120:47–50
  12. Ferro MT, Vazquez-mazariego Y, Ramiro S, et al.  Triplication of 1q in Fanconi anemia. Cancer Genet. Cytogenet. 2001;127:38–41
  13. Nakamura Y, Komano H, Nakauchi H. Two alternative forms of cDNA encoding CD34. Exp. Hematol. 1993;21:236–242

PII: S0145-2126(02)00038-3

Leukemia Research
Volume 26, Issue 11 , Pages 1047-1049 , November 2002

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