Leukemia Research
Volume 26, Issue 8 , Pages 771-774 , August 2002

Lymphoid blastic crisis of chronic myelogenous leukaemia with inv(16)(p13;q22)

  • Kazuya Tsuboi

      Affiliations

    • Second Department of Internal Medicine, Nagoya City University Medical School, Mizuho-ku, Nagoya 467-8601, Japan
    • Department of Internal Medicine, Division of Haematology, Aichi Medical University, Nagakute-cho, Aichi-gun, Aichi 480-1195, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81-561-62-3311; fax: +81-561-63-3401
    • ,
  • Hirokazu Komatsu

      Affiliations

    • Second Department of Internal Medicine, Nagoya City University Medical School, Mizuho-ku, Nagoya 467-8601, Japan
    • ,
  • Hiroshi Miwa

      Affiliations

    • Department of Internal Medicine, Division of Haematology, Aichi Medical University, Nagakute-cho, Aichi-gun, Aichi 480-1195, Japan
    • ,
  • Shinsuke Iida

      Affiliations

    • Second Department of Internal Medicine, Nagoya City University Medical School, Mizuho-ku, Nagoya 467-8601, Japan
    • ,
  • Shogo Banno

      Affiliations

    • Second Department of Internal Medicine, Nagoya City University Medical School, Mizuho-ku, Nagoya 467-8601, Japan
    • ,
  • Atsushi Wakita

      Affiliations

    • Second Department of Internal Medicine, Nagoya City University Medical School, Mizuho-ku, Nagoya 467-8601, Japan
    • ,
  • Masakazu Nitta

      Affiliations

    • Department of Internal Medicine, Division of Haematology, Aichi Medical University, Nagakute-cho, Aichi-gun, Aichi 480-1195, Japan
    • ,
  • Ryuzo Ueda

      Affiliations

    • Second Department of Internal Medicine, Nagoya City University Medical School, Mizuho-ku, Nagoya 467-8601, Japan

Received 20 September 2001 ,Accepted 1 November 2001.

References 

  1. Le Beau MM, Larson RA, Bitter MA. Association of an inversion of chromosome 16 with abnormal marrow eosinophilia in acute melomonocytic leukaemia. N. Engl. J. Med. 1983;309:630–636
  2. Abbondanzo SL, Gray RG, Whang-Peng J, Jacobson RJ. A myelodysplastic syndrome with eosinophilia terminating in acute nonlymphocytic leukemia, associated with an abnormal chromosome 16. Arch Pathol. Lab. Med. 1987;111:330–332
  3. Miyamoto T, Akashi K, Hayashi S, Oogami A, Okamura T, Iwasaki H, et al.  Pericentric inversion of chromosome 16 and eosinophilia in chronic myelomonocytic leukemia. Cancer Genet. Cytogenet. 1997;94(2):99–102
  4. Mecucci C, Noens L, Aventin A. Philadelphia-positive acute myelomonocytic leukemia with inversion of chromosome 16 and eosinobasophils. Am. J. Hematol. 1988;27:69–71
  5. You-Sheng L, Hayhoe FGJ. Ph1 chromosome positive acute myelomonocytic leukemia with inverted chromosome 16. Br. J. Haematol. 1988;69:576
  6. Myint H, Ross FM, Hall JL, Hamblin TJ. Early transformation to acute myeloblastic leukaemia with the acquisition of inv(16) in Ph positive chronic granulocytic leukaemia. Leuk. Res. 1997;21(5):473–474
  7. Colovic M, Jankovic G, Bila J, Djordevic V, Wiernik PH. Inversion of chromosome 16 in accelerated phase of chronic myeloid leukaemia: report of a case and review of the literature. Med. Oncol. 1998;15(3):199–201
  8. Enright H, Weisdorf D, Peterson L, Rydell RE, Kaplan ME, Arthur DC, et al.  Inversion of chromosome 16 and dysplastic eosinophils in accelerated phase of chronic myeloid leukemia. Leukemia. 1992;6(5):381–384
  9. Asou N, Sanada I, Tanaka K, Hidaka M, Suzushima H, Matsuzaki H, et al.  Inversion of chromosome 16 and bone marrow eosinophilia in a myelomonocytic transformation of chronic myeloid leukemia. Cancer Genet. Cytogenet. 1992;61(2):197–200
  10. Heim S, Christensen BE, Fioretos T, Sorensen AG, Pedersen NT. Acute myelomonocytic leukemia with inv(16)(p13q22) complicating Philadelphia chromosome positive chronic myeloid leukemia. Cancer Genet. Cytogenet. 1992;59(1):35–38
  11. Evers JP, Bagg A, Himoe E, Zwiebel JA, Jacobson RJ. Temporal association of marrow eosinophilia with inversion of chromosome 16 in recurrent blast crisis of chronic myelogenous leukemia. Cancer Genet. Cytogenet. 1992;62(2):134–139
  12. Liu P, Claxton DF, Marlton P, Hajra A, Siciliano J, Freedman M, et al.  Identification of yeast artificial chromosomes containing the inversion 16p-arm breakpoint associated with acute myelomonocytic leukemia. Blood. 1993;82(3):716–721
  13. Liu P, Tarle SA, Hajra A, et al.  Fusion between transcription factor CBFb/PEBP2b and a myosin heavy gene in acute myeloid leukaemia. Science. 1993;261:1041–1044
  14. Shurtleff S, Meyers S, Hiebert S, Raimondi S, Head D, Willman C, et al.  Heterogeneity in CBFb/MYH11 fusion messages encoded by the inv(16)(p13q22) and the t(16;16)(p13;q22) in acute myelogenous leukemia. Blood. 1995;85(12):3695–3703
  15. Poirel H, Weiss I, Rack K, Troussard X, Veil A, Valensi F, et al.  Detction of the chromosome 16 CBFb-MYH11 fusion transcript in myelomonocytic leukemias. Blood. 1995;85(5):1313–1322
  16. Liu P, Hajra A, Wijmenga C, Collins FS. Molecular pathogenesis of the chromosome 16 inversion in the M4Eo subtype of acute myeloid leukemia. Blood. 1995;85(9):2289–2302
  17. Reijden B, Lombardo M, Dauwerse H, Giles R, Mühlematter D, Bellomo M, et al.  RT-PCR diagnosis of patients with acute nonlymphocytic leukemia and inv(16)(p13q22) and identification of new alternative splicing in CBFb-MYH11 transcripts. Blood. 1995;86(1):277–282
  18. Marlton P, Claxton DF, Liu P, Estey EH, Beran M, Lebeau M, et al.  Molecular characterisation of 16p deletions associated with inversion 16 defines the critical fusion for leukemogenesis. Blood. 1995;85(3):772–779

PII: S0145-2126(01)00199-0

Leukemia Research
Volume 26, Issue 8 , Pages 771-774 , August 2002

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