« Previous
Next »
Leukemia Research
Volume 26, Issue 7
, Pages 621-629
, July 2002
Potential mechanisms of resistance to cytarabine in AML patients
References
- . Induction of MDR1 gene expression by anthracycline analogues in a human drug resistant leukaemia cell line. Br J Cancer. 1999;79:831–837
- . Characterization of the M(r) 190,000 multidrug resistance protein (MRP) in drug-selected and transfected human tumor cell. Cancer Res. 1995;55:102–110
- Overexpression of a M(r) 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance. Cancer Res. 1993;53:1475–1479
- Clinical relevance of P-glycoprotein expression in de novo acute myeloid leukemia. Blood. 1996;87:1997–2004
- Overexpression of the major vault transporter protein lung-resistance protein predicts treatment outcome in acute myeloid leukemia. Blood. 1996;87:2464–2469
- P-glycoprotein, lung resistance-related protein and multidrug resistance associated protein in de novo acute non-lymphocytic leukaemias: biological and clinical implications. Br J Haematol. 1999;104:328–335
-
.
Correlation of cytotoxicity with incorporation of ara-C into DNA.
J Biol Chem. 1980;255:8900–8997
- . Nucleoside analogues: mechanisms of drug resistance and reversal strategies. Leukemia. 2001;15:875–890
- . Effect of ara-C incorporation on deoxyribonucleic acid synthesis in cells. Biochem Pharmacol. 1982;31:2937–2940
- . Transport and metabolism of deoxycytidine and 1-β-d- arabinofuranosylcytosine into cultured Novikoff rat hepatoma cells, relationship to phosphorylation and regulation of triphosphate synthesis. Cancer Res. 1978;38:978–989
- . Cytosine arabinoside transport and metabolism in acute leukemias and T cell lymphoblastic lymphoma. J Clin Invest. 1985;75:632–642
-
.
The role of nucleoside transport in anticancer drug resistance.
Drug Resistance Updates. 1998;1:310–324
-
.
Molecular identification of the equilibrative NBMPR-sensitive (es) nucleoside transporter and demonstration of an equilibrative NBMPR-insensitive (ei) transport activity in human erythroleukemia (K562) cells.
Neuropharmacol. 1997;36:1167–1179
- . Deoxycytidine kinase: properties of the enzyme from human leukemic granulocytes. Blood. 1975;46:791–803
- . Saturation of ara-CTP accumulation during high-dose ara-C therapy: pharmacologic rationale for intermediate-dose ara-C. Semin Oncol. 1987;14:159–166
- . Human cytidine deaminase: purification of enzyme, cloning and expression of its complementary DNA. Cancer Res. 1994;54:5401–5407
- Common resistance mechanisms to deoxynucleoside analogues in variants of the human erythroleukaemic line K562. Br J Haematol. 1999;106:78–85
-
.
Sensitivity of HEL and K562 cell lines to topotecan correlates with the level of topoisomerase I expression activity.
Proc Am Assoc Cancer Res. 1999;40:A719
- . A possible role for topoisomerase II in cell death and N-phosphonoacetyl-l-aspartate-resistance frequency and its enhancement by 1-β-d-arabinofuranosyl cytosine and 5-fluoro-2′-deoxyuridine. Mutat Res. 1997;384:89–106
-
Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French–American–British Cooperative Group.
Ann Int Med. 1985;103:620–625
- . The role of 5′-nucleotidase in therapy-resistance of childhood leukemia. Med. Hypotheses. 1988;27:77–80
- Hypoxanthine-guanine phosphoribosyl-transferase in childhood leukemia: relation with immunophenotype, in vitro drug resistance and clinical prognosis. Int J Cancer. 1992;51:213–217
- . Prognostic value of 5′-nucleotidase in acute lymphoblastic leukemia with the common-ALL phenotype. Leuk Res. 1985;9:1227–1229
- . Phosphorylation of 2-chlorodeoxyadenosine (CdA) in extracts of peripheral blood mononuclear cells of leukaemic patients. Br J Haematol. 1994;87:715–718
- . Mammalian deoxyribonucleoside kinases. Pharmacol Ther. 1995;67:155–186
- . Relationship of deoxycytidine kinase and cytoplasmic 5′-nucleotidase to the chemotherapeutic efficacy of 2-chlorodeoxyadenosine. Blood. 1993;81:597–601
- Expression of high km 5′-nucleotidase in leukemic blasts is an independent prognostic factor in adults with acute myeloid leukemia. Blood. 2001;98:1922–1926
- . Nucleoside transporters: molecular biology and implications for therapeutic development. Mol Med Today. 1999;5:216–224
- . Sensitivity of acute leukemia cells to cytarabine is a correlate of cellular es nucleoside transporter site content measured by flow cytometry with SAENTA-fluorescein. Blood. 1997;90:346–353
- Es nucleoside transporter content of acute leukemia cells: role in cell sensitivity to cytarabine (ara-C). Leuk Lymphoma. 1998;32:45–54
- Activity of thymidine kinase and of polymerase α as well as activity and gene expression of deoxycytidine deaminase in leukemic blasts are correlated with clinical response in the setting of granulocyte-macrophage colony-stimulating factor-based priming before and during TAD-9 induction therapy in acute myeloid leukemia. Blood. 1997;90:1968–1976
- . Mechanisms of resistance of human acute leukaemia cells to cytosine arabinoside. Br J Haematol. 1974;27:39–46
- . Cytidine deaminase and the development of resistance to arabinosyl cytosine. Nat New Biol. 1971;233:109–110
- . Deoxycytidine kinase and deoxycytidine deaminase values correspond closely to clinical response to cytosine arabinoside remission induction therapy in patients with acute myelogenous leukemia. Semin Oncol. 1987;14:257–261
- . Structural and functional analysis of the cytidine deaminase gene in patients with acute myeloid leukaemia. Br J Haematol. 1998;103:1096–1103
- Constitutive overexpression of the cytidine deaminase gene confers resistance to cytosine arabinoside in vitro. Leukemia. 1996;10:1919–1924
- Topoisomerase II levels and drug sensitivity in adult acute myelogenous leukemia. Blood. 1994;83:517–530
- Five putative drug resistance parameters (MDR1/P-glycoprotein, MDR-associated protein, glutathione-S-transferase, bcl-2 and topoisomerase II α) in 57 newly diagnosed acute myeloid leukaemias. Swiss Group for Clinical Cancer Research (SAKK). Eur J Haematol. 1997;59:206–215
PII: S0145-2126(01)00184-9
© 2002 Elsevier Science Ltd. All rights reserved.
« Previous
Next »
Leukemia Research
Volume 26, Issue 7
, Pages 621-629
, July 2002
