Leukemia Research
Volume 26, Issue 3 , Pages 235-240 , March 2002

Primary myelodysplastic syndrome with normal cytogenetics: utility of ‘FISH panel testing’ and M-FISH

Received 19 February 2001 ,Accepted 10 June 2001.

References 

  1. Aul C, Gattermann N, Schneider W. Epidemiological and etiological aspects of myelodysplastic syndromes. Leuk. Lymphoma. 1995;16:247–262
  2. Vallespi T, Imbert M, Mecucci C, Preudhomme C, Fenaux P. Diagnosis, classification, and cytogenetics of myelodysplastic syndromes. Haematologica. 1998;83:258–275
  3. Fenaux P, Morel P, Lai J. Cytogenetics of myelodysplastic syndromes. Semin. Hematol. 1996;33:127–138
  4. Mecucci C. Molecular features of primary MDS with cytogenetic changes. Leuk. Res. 1998;22:293–302
  5. Willman C. Molecular genetic features of myelodysplastic syndromes (MDS). Leukemia. 1998;12(Suppl. 1):S2–S6
  6. Spurbeck J, Zinsmeister A, Meyer K, Jalal S. Dynamics of chromosome spreading. Am. J. Med. Genet. 1996;61:387–393
  7. Law M, Jalal S. M-FISH technique: how to set up and analyze. J. Assoc. Genet. Technol. 2000;26:51–53
  8. Schad CR, Hanson CA, Paietta E, Casper J, Jalal SM, Dewald GW. Efficacy of fluorescence in situ hybridization for detecting PML/RARA gene fusion in treated and untreated acute promyelocytic leukemia. Mayo Clin. Proc. 1994;69:1047–1053
  9. van der Plas D, Grosveld G, Hagemeijer A. Review of clinical, cytogenetic and molecular aspects of Ph-negative CML. Cancer Genet. Cytogenet. 1991;52:143–156
  10. Spathas D, Steward J, Singer I, Theriault A, Bovey M, Connor J. Detection of t(12;21) in childhood acute lymphoblastic leukemia by fluorescence in situ hybridization. Cancer Genet. Cytogenet. 1999;110:7–13
  11. Jotterand M, Parlier V. Diagnostic and prognostic significance of cytogenetics in adult primary myelodysplastic syndromes. Leuk. Lymphoma. 1996;23:253–266
  12. Juneau A, Kaehler M, Christensen ER, Schad CR, Zinsmeister AR, Lust J, et al. Detection of RB1 deletions by fluorescence in situ hybridization in malignant hematologic disorders. Cancer Genet. Cytogenet. 1998;103:117–123
  13. Jalal SM, Law ME. Utility of multicolor fluorescent in situ hybridization in clinical cytogenetics. Genet. Med. 1999;1(5):181–186

PII: S0145-2126(01)00117-5

Leukemia Research
Volume 26, Issue 3 , Pages 235-240 , March 2002