« Previous
Next »
Leukemia Research
Volume 25, Issue 9
, Pages 813-820
, 1 September 2001
Pyridinyl imidazole inhibitor SB203580 activates p44/42 mitogen-activated protein kinase and induces the differentiation of human myeloid leukemia cells
References
- . Induction of erythroid differentiation of K562 human leukemic cells by herbimycin A, an inhibitor of tyrosine kinase activity. Cancer Res. 1989;49:331
- . Induction of differentiation of human leukemia cells by inhibitors of myosin light chain kinase. FEBS Lett. 1991;287:175
- . Effects of inhibitors of tyrosine kinase activity and/or phosphatidylinositol turnover on differentiation of some human myelomonocytic leukemia cells. Leuk. Res. 1991;15:701
- . Staurosporine, a novel protein kinase inhibitor, enhances HL-60-cell differentiation induced by various compounds. Exp. Hematol. 1988;16:42
- . Retinoic acid induced mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK) kinase-dependent MAP kinase activation needed to elicit HL-60 cell differentiation and growth arrest. Cancer Res. 1998;58:3163
- . Activation of raf-1 and mitogen-activated protein kinases during monocytic differentiation of human myeloid leukemia cells. J. Biol. Chem. 1994;269:872
- . Phosphatidylinositol 3-kinase in HL-60 nuclei is bound to the nuclear matrix and increases during granulocytic differentiation. Biochem. Biophys. Res. Commun. 1998;253:346
- . Retinoic acid induces selective expression of phosphoinositide-3-kinase γ in myelomonocytic U937 cells. Cell Growth Differ. 1999;10:447
- . Antisense oligonucleotides targeted against protein kinase Cß and CβII block 1,25-(OH)2D3-induced differentiation. J. Biol. Chem. 1998;273:19587
- . Functional role for protein kinase Cß as a regulator of stress-activated protein kinase activation and monocytic differentiation of myeloid leukemia cells. Mol. Cell Biol. 1999;19:461
- . Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture. Nature. 1977;270:347
- . Hematopoietic cytokine dependent differentiation to eosinophils and neutrophils in newly established acute promyelocytic leukemia cell line with t (15; 17). Exp. Hematol. 1998;26:135
-
.
Immunology of leukemic cells.
In:
Grunz F, Henderson E editor. Leukemia. New York: Grune and Stratton; 1982;p. 119
- . Establishment and characterization of a human acute monocytic leukemia cell line (THP-1). Int. J. Cancer. 1980;26:171
- . Establishment and characterization of a human histiocytic lymphoma cell line. Int. J. Cancer. 1976;17:565
- . Enhancement of activity of 1α,25-dihydroxyvitamin D3 for growth inhibition and differentiation induction of human myelomonocytic leukemia cells by tretinoin tocoferil, an α-tocopherol ester of all-trans retinoic acid. Blood. 1996;87:3384
- . Induction of differentiation of human myeloid leukemia HL-60 cells by novel pyrimidine nucleoside analogs. Biochim. Biophys. Acta. 1991;1094:1
- . Vesnarinone and glucocorticoids cooperatively induce G1 arrest and have an antitumour effect on human non-small cell lung carcinoma cells grown in nude mice. Br. J. Cancer. 1999;80:96
- . Induction of differentiation of cultured human promyelocytic leukemia cells by retinoids. Biochem. Biophys. Res. Commun. 1980;95:507
- . Inhibition of IL-1-induced IL-6 production by synthetic retinoids. Biochem. Biophys. Res. Commun. 1997;231:243
- . A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket. Nat. Struct. Biol. 1997;4:311
- . Molecular basis for p38 protein kinase inhibitor specificity. Biochemistry. 1998;37:16573
- . p38 mitogen- activated protein kinase inhibitors-Mechanisms and therapeutic potentials. Pharmacol. Ther. 1999;82:389
- . SB203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stress and interleukin-1. FEBS Lett. 1995;364:229
- . Inhibition of p38 MAP kinase activity up-regulates multiple MAP kinase pathways and potentiates 1,25-dihydroxyvitamin D3-induced differentiation of human leukemia HL60 cells. Exp. Cell Res. 2000;258:425
- . Effect of SB203580 on the activity of c-Raf in vitro and in vivo. Oncogene. 1999;18:2047
- . The p38 MAP kinase inhibitor SB203580 enhances nuclear factor-kappa B transcriptional activity by a non-specific effect upon the ERK pathway. Br. J. Pharmacol. 2000;131:99
- . Induction of differentiation of human myeloid leukemia cells by 2′-deoxycoformycin in combination with 2′-deoxyadenosine. Biochem. Biophys. Res. Commun. 1997;238:100
-
.
Adenosine analogs as possible differentiation-inducing agents against acute myeloid leukemia.
Leuk. Lymph. 1999;34:261
- . Myeloid and monocytoid leukemia cells have different sensitivity to differentiation-inducing activity of deoxyadenosine analogs. Leuk. Res. 2000;24:1
- . Molecular determinants that mediate selective activation of p38 MAP kinase isoforms. EMBO J. 2000;19:1301
PII: S0145-2126(01)00026-1
© 2001 Elsevier Science Ltd. All rights reserved.
« Previous
Next »
Leukemia Research
Volume 25, Issue 9
, Pages 813-820
, 1 September 2001
