Leukemia Research
Volume 25, Issue 9 , Pages 735-739 , 1 September 2001

Chromosome 7 monosomy and deletions in myeloproliferative diseases

  • Pasquale Tripputi

      Affiliations

    • Department of Medicine, Surgery and Dentistry, University of Milan, Ospedale San Paolo via A. di Rudinı̀ 8, 20142 Milano, Italy
    • Corresponding Author InformationCorresponding author. Tel.: +39-02-8135366; fax: +39-02-89122032
  • ,
  • Barbara Cassani

      Affiliations

    • Department of Medicine, Surgery and Dentistry, University of Milan, Ospedale San Paolo via A. di Rudinı̀ 8, 20142 Milano, Italy
  • ,
  • Rosamaria Alfano

      Affiliations

    • Department of Medicine, Surgery and Dentistry, University of Milan, Ospedale San Paolo via A. di Rudinı̀ 8, 20142 Milano, Italy
  • ,
  • Daniela Graziani

      Affiliations

    • Department of Medicine, Surgery and Dentistry, University of Milan, Ospedale San Paolo via A. di Rudinı̀ 8, 20142 Milano, Italy
  • ,
  • Daniela Cigognini

      Affiliations

    • Department of Clinical Medicine, University of Milano–Bicocca Via Donizetti 106, 20052 Monza, Italy
  • ,
  • Patrizia Doi

      Affiliations

    • Department of Medicine, Surgery and Dentistry, University of Milan, Ospedale San Paolo via A. di Rudinı̀ 8, 20142 Milano, Italy
  • ,
  • Monica Bignotto

      Affiliations

    • Department of Medicine, Surgery and Dentistry, University of Milan, Ospedale San Paolo via A. di Rudinı̀ 8, 20142 Milano, Italy
  • ,
  • Gianmarco Corneo

      Affiliations

    • Department of Clinical Medicine, University of Milano–Bicocca Via Donizetti 106, 20052 Monza, Italy
  • ,
  • Guido Coggi

      Affiliations

    • Department of Medicine, Surgery and Dentistry, University of Milan, Ospedale San Paolo via A. di Rudinı̀ 8, 20142 Milano, Italy

Received 8 August 2000 ,Accepted 30 December 2000.

References 

  1. Pedersen-Bjergaard J, Andersen MK, Christiansen DH. Therapy-related acute myeloid leukemia and myelodysplasia after high-dose chemotherapy and autologous stem cell trasplantation. Blood. 2000;95:3273–3279
  2. Le Beau MM, Espinosa III R, Davis M, Eisembart DJ, Larson AR, Green DE. Cytogenetic and molecular delineation of a region of chromosome 7 commonly deleted in malignant myeloid diseases. Blood. 1996;88:1930–1935
  3. Liang H, Fairman J, Claxton DF, Nowell PC, Green ED, Nagarajan L. Molecular anatomy of ch 7q deletions in myeloid neoplasms: evidence for multiple critical loci. Proc. Natl. Acad. Sci. USA. 1998;95:3781–3785
  4. Weinberg RA. Tumor suppressor genes. Science. 1991;254:1138
  5. Dabaja BS, Faderl S, Thomas D, Cortes J, O'Brien S, Nasr F, et al.  Deletions and losses in chromosomes 5 or 7 in adult acute lymphocytic leukemia: incidence, associations and implications. Leukemia. 1999;13:869–872
  6. Anastasi J. Molecular cytogenetics and the myelodysplastic syndromes. Leukemia Res. 1996;20:559–562
  7. Takahashi S, Shan LA, Ritland RS, Delacey AK, Bostwick GD, Lieber MM. Frequent loss of heterozygosity at 7q31.1 in primary prostate cancer is associated with tumor aggressiveness and progression. Cancer Res. 1995;55:4114–4119
  8. Tripputi P, Emanuel BS, Croce CM, Green L, Stein GS, Stein JL. Human histone genes map to multiple chromosomes. Proc. Natl. Acad. Sci. USA. 1986;83:3185–3188
  9. Mitelman F, editor. ISCN guidelines for cancer cytogenetics: Supplement to an international system for a human genetics nomenclature. Basel: Karger, 1991.
  10. Tripputi P, Guerin S, Moore DD. Two mechanisms for extinction of gene expression in hybrid cells. Science. 1988;241:1205–1208
  11. Tripputi P, Bacciocchi G, Accolla SR, Mantero G, De Bellis G, Manoni M, et al.  Detection of human chromosomes in somatic cell hybrids by PCR analysis. Cytogenet. Cell. Genet. 1993;62:1–4
  12. Canzian F, Salovaara R, Hemminkia A, Chadwick RB, Aaltonen LA, de la Chapelle A. Semiautomated assessement of loss of heterozigosity and replication error in tumor. Cancer Res. 1996;56:3331–3337
  13. Tripputi P, Graziani D, Alfano RM, Cassani B, Coggi G. A common T/C polymorphism in the promoter region of the beta T-cell receptor gene. Mol. Cell. Probes. 2000;14:195–197
  14. Scarisbrick JJ, Woolford JA, Russel-Jones R, Whittaker JS. Loss of heterozygosity on 10q and microsatellite instability in advanced stages of primary cutaneous T-cell lymphoma and possible association with homozygous deletion of PTEN. Blood. 2000;95:2937–2942
  15. Tsukamoto K, Noriko I, Yoshimoto M, Kasumi F, Akiyama F, Sakamoto G, et al.  Allelic loss on chromosome 1p is associated with progression and lymph node metastasis of primary breast carcinoma. Cancer. 1998;82:317–322
  16. Saretzki G, Hofmann U, Rohlke P, Psille R, Gaigal T, Keller G, et al.  Identification of allelic losses in benign, borderline, and invasive epithelial ovarian tumors and correlation with clinical outcome. Cancer. 1997;80:1241–1249

PII: S0145-2126(01)00012-1

Leukemia Research
Volume 25, Issue 9 , Pages 735-739 , 1 September 2001