Leukemia Research
Volume 24, Issue 7 , Pages 595-596 , July 2000

Myelodysplastic syndrome and aplastic anemia — diagnostic and conceptual uncertainties

Received 4 February 2000 ,Accepted 4 February 2000.

References 

  1. Tichelli A, Gratwohl A, Wursch A, et al.  Late haematological complications in severe aplastic anaemia. Br. J. Haematol. 1988;69:413–418
  2. Molldrem JJ, Caples M, Mavroudis D, et al.  Antithymocyte globulin for patients with myelodysplastic syndrome. Br. J. Haematol. 1997;99:699–705
  3. Jonasova A, Neuwirtova R, Cermak J, et al.  Cyclosporin A therapy in hypoplastic MDS patients and certain refractory anaemias without hypoplastic bone marrow. Br. J. Haematol. 1998;100:304–309
  4. Young NS, Maciejewski J. The pathophysiology of acquired aplastic anemia. New Engl. J. Med. 1997;336:1365–12372
  5. Molldrem JJ, Jiang YZ, Stetler-Stevenson MA, et al.  Haematological response of patients with myelodysplastic syndrome to antithymocyte globulin is associated with a loss of lymphocyte-mediated inhibition of CFU-GM and alterations in T-cell receptor V beta profiles. Br. J. Haematol. 1998;102:1314–1322
  6. Dunn DE, Tanawattanacharoen P, Boccuni P, et al.  Paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure syndromes. Ann. Intern. Med. 1999;131:401–408
  7. Iwanga M, Furukawa K, Amenomori T, et al.  Paroxysmal nocturnal haemoglobinuria clones in patients with myelodysplastic syndromes. Br. J. Haematol. 1998;102:465–474
  8. Otawa M, Kawanishi Y, Iwase O, Shoji N, Miyazawa K, Ohyashi K. Comparative multi-color flow cymetric analysis of cell surface anntigens in bone marrow hematopoietic progenitors between refractoryanemia and aplastic anemia. Leuk. Res. 2000;24:359–366
  9. Orazi A, Albitar M, Heerema NA. et al: Hypoplastic myelodysplastic syndromes can be distinguished from acquired aplastic anemia by CD34 and PCNA immunostaining of bone marrow biopsy specimens. Am. J. Clin. Pathol. 1997;107:268–274

PII: S0145-2126(00)00026-6

Leukemia Research
Volume 24, Issue 7 , Pages 595-596 , July 2000

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